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The findings of this study are in support of a role of aberrant signalling of the MAPK pathway in the pathogenesis of low-grade serous testicular neoplasms, and provide a genetic link between low-grade testicular and ovarian serous tumours.

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We read with interest the significance of the different types of seminal vesicle invasion described in the recent paper by Kristiansen et al The three types of invasion of the seminal vesicle are well recognised, but there is a much rarer method of invasion, that is by intraductal cancer spreading up into the seminal vesicles via the ejaculatory ducts. This method has been reported in a single case report but was not seen in the series by Kristiansen . This article is protected by copyright. All rights reserved.