Cytoreductive surgery and HIPEC seem to be associated with promising results in patients with recurrent ovarian cancer. Large international prospective studies are required to further quantify the true efficacy of HIPEC and identify the optimal treatment protocol for a maximum survival benefit.

IntroductionHealthcare workers' wellbeing is critical to the NHS. Night shifts have a big impact on their physical and mental health. Recently there has been national funding for rest facilities. MethodsAn EnergyPod was installed in the acute medical unit. The study comprised two surveys: one quantitative survey performed prior to the pod introduction and repeated 3 months after; and one qualitative survey performed immediately after pod use. ResultsWe observed more staff taking breaks of 30 minutes after the pod introduction (37% before vs 69% after). Of users, 81% felt more alert and 83% were more energised. Half of the respondents felt more able to drive after use.The feedback showed three themes: appreciation of designated space away from clinical areas, relaxation and improved interdisciplinary cohesion. ConclusionWe have shown consistent data that rest is important for wellbeing. We recommend the use of EnergyPods in high acuity areas.

Background: Giant cell arteritis/temporal arteritis (GCA) is an inflammatory condition that affects large to medium vessels such as the aorta and its primary branches. Patients classically present with fatigue, fever, headache, jaw claudication and in severe cases, may suffer either transient (amaurosis fugax) or permanent visual loss. The reference standard for diagnosis is the temporal artery biopsy (TAB) and the mainstay of treatment is with immunosuppression. Our patient JG, presented with a range of non-specific symptoms that mimicked generalised sepsis, but was ultimately diagnosed with GCA through effective, methodical multi-disciplinary team (MDT) work. Clinical case: JG, an 81 year old gentleman, presented acutely with a 3-4 weeks history of fatigue, lethargy, pyrexia and a marked inflammatory response suggestive of a sepsis but without a clear primary source or clinical features of vasculitis. His inflammatory markers were markedly raised although his erythrocyte sedimentation rate (ESR) was not elevated. He was initially treated for sepsis of unknown origin however, body imaging after admission suggested a possible infection around a previous aortic graft site. This was refuted in subsequent 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET/CT) scanning. Microbiological, parasitic, as well as autoimmune assays were unremarkable. He underwent a TAB which was diagnostic for GCA and as a result, was started on oral corticosteroids with immediate symptom relief. He was discharged and followed up on an outpatient basis. Conclusions: This case highlights how a vasculitis can present with a range of non-specific symptoms that may resemble a fever of unknown origin (FUO)/sepsis that can lead to a delay in making the correct diagnosis. It also highlights the importance of considering a diagnosis of vasculitis in patients who present with a FUO where there is no clear focus of infection. Delays in diagnosis and management of these conditions can potentially lead to significant irreversible morbidity.

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Irrespective of applying lubricants between high-speed machinery’s shafts and Air-foil bearings (AFBs), wear and friction remain troublesome. Hence, the present study sought novel bare foil and equivalent nanocomposites to form a coating system that could mitigatly lower frictional wear between high-speed machinery’s shafts and Air-foil bearings (AFBs). Bare and coated foils were supplied on rectengular dimensions of 15 × 15 × 5mm3. Mechanical properties were characterized by Instron 3384 testing machine. Universal Tribometer s/n : RTEC2441, USA was utilized for tribological measurements at room temperature. Surface morphologies were examined by Scanning electron microscopy (SEM). Higher hardness and young modulus values were recorded from coated foils. On the other hand, specific wear rates were relatively low from coated foils. Furthermore, abrasive wear index was higher from the F2 coated foil. Friction coeffients were also lower from the coated foils under all engaged tribological conditions. Highly ruptured SEM morphologies were noticed from the bare foil. Nonetheless, mild and negligible aggressions were discovered from the surfaces of nano-coated foils.