In evaluating partial renal infarction, a strong clinical suspicion is necessary. We found a history of dysrhythmia or other cardiac disease, the presence of abdominal or flank pain, fever with an elevated white cell count, and an elevated LDH to be clinically significant, and their presence should alert the clinician to the possibility of renal infarction. Once a degree of suspicion exists, early evaluation with CT should speed the diagnosis and effect decreased morbidity.
Complete renal embolization is a viable alternative to nephrectomy in patients with poorly functioning kidneys who present with pain or bleeding and in those who are poor operative candidates. This procedure is safe, reliable and minimally invasive with few long-term sequelae, and it is well tolerated.
Capacitation of spermatozoa is essential for fertilization, and can be induced by various agents or biological fluids. Previous reports have shown that foetal cord serum (FCS) and the superoxide anion trigger human sperm hyperactivation and capacitation, and that superoxide dismutase (SOD) prevents these processes. We investigated: (1) the capacity of seminal plasma (SP) and follicular fluid (FF) (whole, or fractionated into high and low molecular weight components), in the presence or absence of SOD, to induce the spontaneous acrosome reaction (no stimulant needed, AR) and capacitation (as measured by the lysophosphatidyl-choline-induced AR, LPC-AR); (2) a possible relationship between the levels of AR and capacitation obtained with these biological fluids and the superoxide scavenging capacity of the same fluids. The highest levels of LPC-AR were obtained with FF ultrafiltrate (48 +/- 6%), followed by SP ultrafiltrate (31.9 +/- 0.8%), FF (30 +/- 5%), dialysed FF (27 +/- 4%), and finally, by FCS ultrafiltrate (23 +/- 1%), SP (21 +/- 1%) and dialysed SP (18.9 +/- 0.8%). A similar order of potency for the fluids existed when sperm AR was studied, the levels of AR observed ranging from 16 +/- 2% to 5.3 +/- 0.8% after incubation with FF ultrafiltrate and SP respectively. None of these treatments had detrimental effects on sperm motility. In the presence of SOD, there was always an important reduction (52-86%) of the AR and LPC-AR observed.(ABSTRACT TRUNCATED AT 250 WORDS)
Complete renal embolization is a viable alternative to nephrectomy in patients with poorly functioning kidneys who present with pain or bleeding and in those who are poor operative candidates. This procedure is safe, reliable and minimally invasive with few long-term sequelae, and it is well tolerated.
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