Objective Laser/photocoagulation criteria for retinopathy of prematurity (ROP) are generally universal, with > 90% anatomic success reported in varied settings. Outcomes in the Philippines, a developing/lower-middle income nation, were examined. Results This single-center retrospective chart review covered years 2014 and 2015. Of 214 infants screened, 64 had any ROP. Thirty-four were treated, and 20 had documented outcomes. Only 15 of 25 eyes (8 infants) with laser treatment-requiring ROP were successes (60%). All infants had Type 1 ROP except one with Aggressive Posterior ROP. Seven infants with bilateral “Milder than Type 1” ROP were treated successfully. Type 1 ROP treatment failures versus successes did not differ significantly in birth weight (1009 g vs. 1112.86 g, p = .5152), birth age of gestation (27.74 vs. 28.49 weeks, p = .3290), and, delay in first screening (6.74 vs. 5 weeks, p = .4649). Poorer outcomes of laser treatment-requiring ROP were documented here compared with elsewhere in the world. Variables/risk factors examined were limited and human error was not systematically considered. Subsequent studies validating this trend should incorporate other clinical (e.g. maternal/neonatal risk factors) and environmental differences that might drive pathology and treatment response in this multifactorial disease. Adherence to protocols gains importance given the widespread delay and early loss to follow-up observed. Electronic supplementary material The online version of this article (10.1186/s13104-019-4303-3) contains supplementary material, which is available to authorized users.

Library of Congress Cataloging-in-Publication

SCPG avoids time-consuming and costly life cycle assessments, yet provides the framework to map clinical care. The change from warfarin to DOACs reduced the CF of the EDCCV care pathway for patients attending our hospital. ■

PURPOSE: There are currently no published studies on the outcomes of keratoplasty in the Philippines.  This study aimed to report graft survival rates at years 1, 3, and 5 after surgery, visual outcomes, and causes of graft failure among private patients of corneal surgeons in Metropolitan Manila receiving tissue from a single local eye bank in the period 2008-2012.  DESIGN: Retrospective cohort, multicenter study. METHODS: POPULATION: Private patients of Metro Manila corneal surgeons, receiving tissue from the Santa Lucia International Eye Bank of Manila in 2008-2012.  241 of 593 yielded sufficiently complete data sets. PROCEDURE: Donor and tissue characteristics, pre-op and latest follow-up characteristics/clinical findings were retrieved and processed. Data from the eye bank was merged with follow-up data from surgeons submitted March-October 2014. MAIN OUTCOME MEASURES: Survival rates at 1, 3, and 5 years; best-corrected visual acuity as of latest follow-up; causes of failure. RESULTS:  1-year survival: 90.4%, 3-year: 71.5%, 5-year: ~52.7%. Overall, 43.5% had VA of 20/50 or better, and 25% counting fingers or worse, with variations across diagnoses. CONCLUSION: Though small in sample size and response rate, survival trends parallel studies with larger populations elsewhere. Specific trends like favorable survival in keratoconus were consistent. Indications for surgery have changed little since 2005, but regraft has become the most common indication. Further data collection and completion are required for multivariate analysis on factors regarding survival.  Inflammation, infection, trauma, poor adherence are among the identified reasons for failure.