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We evaluated the use of abciximab (ReoPro), a monoclonal glycoprotein (GP) Ilb/llla inhibitor, in 45 patients and 49 carotid vessels undergoing stent placement f o r neurologically symptomatic, critical lesions of the common undor internal carotid arteries. Our assessments included procedural success and clinical outcomes including stroke, myocardial infarction (MI), neurological death, and bleeding. There were no instunces of minor or major stroke, Q-wave or non-Q-wave MI, thrombocytopenia, or neurological death in the periprocedural in-hospital period immediately poststenting to discharge, nor any neurological events related to the ipsilateral hemisphere or neurological death during follow-up of up to 1 year, 6 months, and 30 days (30,10, and 5 patients, respectively). The hemoglnbidhematocrit levels dropped in two patients, necessitating blood transfusions. Two patients died w t h multiple organ failure, and three more developed a non-Q-wave infarction at 4 months, 2 months, and 3 weeks poststenting, respectively, (J Interven Cardiol 1999; 12:355-362) Address for reprints: Felipe A. CeceAa, M.D., Director. Acute

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