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ObjectiveThe purpose of this study is to determine the impact of demographics and sinonasal comorbidities on the revision rate of functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS).BackgroundAlthough endoscopic sinus surgery (ESS) is often successful in providing long‐term relief for patients suffering from CRS, revision surgery can occur. There is conflicting literature on the impact of race on FESS outcomes.MethodsA single‐center retrospective cohort study of patients that underwent FESS for CRS between January 1, 2015 and June 1, 2021 at a single tertiary care academic center.ResultsA total of 682 patients between the ages of 18 and 89 underwent primary ESS between January 1, 2015 and June 1, 2021 and were included in this study. Of these patients, 388 (56.9%) were female, with an average age of 48.6 ± 16.7. Thirty‐eight patients (5.6%) underwent revision sinus surgery during the study period. Patients that identified as White had significantly lower rates of revision sinus surgery (4.1%) than non‐White patients (10.7%), including those identifying as Asian, Black, multiracial, or other. On multivariate analysis, non‐White race (OR 4.933), polyposis (3.175), and high preoperative SNOT‐22 scores (OR 1.029) were independently associated with revision sinus surgery. The mean preoperative SNOT‐22 for all participants was 39.1 ± 22.0, whereas the mean postoperative SNOT‐22 was 20.6 ± 17.5 (p < 0.001).ConclusionRace plays an important role in outcomes following revision sinus surgery that is independent of location and insurance status. More studies are required to assess the reason race plays an important role in outcomes following revision sinus surgery.Level of EvidenceLevel 3 Laryngoscope, 2023

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