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Does invention belong in the chemistry classroom? This article attempts to answer this question by describing how invention education first took root in a chemistry class at Ridgewood High School in Ridgewood, NJ, and then expanded to other students with diverse interests to find a solution to two worldwide problems: satisfying the need for safe drinking water and reducing plastic waste. Specifically, it describes the students' journey step-by-step during the COVID-19 pandemic to invent a self-sanitizing and sustainable Solar Aqua Tech water bottle. The concept underlying this invention was to quickly produce hydrogen peroxide (H 2 O 2 ), a well-known sanitizing agent, on-demand within the confines of a bottle using only water, dissolved oxygen (O 2 ), and solar power to eliminate pathogens in untreated water. Students had to convert this chemistry classroom concept into reality without a prescription and without knowing if their goal was even attainable. Since the journey did not take a linear path but veered in different directions as unexpected problems arose, the students sought guidance from academics, mentors, and local experts. Along the way, they acquired new knowledge with deepened understanding and overarching perspectives. Success was achieved only after many setbacks. In the end, the sense of accomplishment for finding a solution to two global problems instilled confidence in the students that, with empathy, perseverance, and resilience, they are equipped with essential skills to tackle 21stcentury challenges. Invention, therefore, can be a valuable complement to the standard chemistry curriculum and is unparalleled in sparking a lifelong passion for learning.

The aim of this retrospective, observational study was to determine the impact of low-dose enoxaparin (20 mg) in conjunction with low-dose aspirin on the pregnancy outcome of women with antiphospholipid syndrome and recurrent miscarriage. The study was conducted in a tertiary referral teaching hospital. A total of 35 women with antiphospholipid syndrome were treated with low-dose enoxaparin and aspirin as soon as pregnancy was confirmed. The outcome of pregnancy was analysed. The miscarriage rate was 7/35 (20%) whereas the live birth rate was 28/35 (80%). In conclusion, low-dose (20 mg) enoxaparin in conjunction with low-dose aspirin treatment produced encouraging results. The findings in this study suggest that there is a case for randomized controlled trials to compare low-dose (20 mg) enoxaparin with higher doses.

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