This research investigates the indirect effect of government social protection program on the relationship between quality of care and the quality of life of the people with disability. In addition, the study also tests the direct effect of quality of care and government social protection program on the quality of life of people with disability. Through empirical analysis using SMART-PLS 3.0, we found that government social protection program has insignificant direct effect on the relationship between quality of care and quality of life of people with disability. In addition, both quality of care and government social protection program have direct significant effect on quality of life of people with disability. Our study enriches theoretical and empirical debates on quality of care, government social protection program and quality of life of people with disability. These findings provide managerial implications and research direction.