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International FTD-Genetics Consortium (IFGC), the German Frontotemporal Lobar Degeneration (FTLD) Consortium, and the PRONIA Consortium IMPORTANCE The behavioral and cognitive symptoms of severe psychotic disorders overlap with those seen in dementia. However, shared brain alterations remain disputed, and their relevance for patients in at-risk disease stages has not been explored so far.OBJECTIVE To use machine learning to compare the expression of structural magnetic resonance imaging (MRI) patterns of behavioral-variant frontotemporal dementia (bvFTD), Alzheimer disease (AD), and schizophrenia; estimate predictability in patients with bvFTD and schizophrenia based on sociodemographic, clinical, and biological data; and examine prognostic value, genetic underpinnings, and progression in patients with clinical high-risk (CHR) states for psychosis or recent-onset depression (ROD). DESIGN, SETTING, AND PARTICIPANTS This study included 1870 individuals from 5 cohorts, including (1) patients with bvFTD (n = 108), established AD (n = 44), mild cognitive impairment or early-stage AD (n = 96), schizophrenia (n = 157), or major depression (n = 102) to derive and compare diagnostic patterns and (2) patients with CHR (n = 160) or ROD (n = 161) to test patterns' prognostic relevance and progression. Healthy individuals (n = 1042) were used for age-related and cohort-related data calibration.

Objective This study examines how the interplay of both partners' employment biographies is associated with the within‐couple gender wealth gap in later life in Britain and Western Germany, including married couples born between the 1920s and 1960s. Background Although it is well‐known that women own less personal wealth than their male partners on average, variation in the gender wealth gap across partners' employment constellations and contexts remains unaddressed. Following the life course paradigm, this study theorizes how individual wealth accumulation, within‐couple redistribution processes, and institutional arrangements shape the within‐couple gender wealth gap in later life. Method The analyses rely on retrospective employment and prospective survey data from Britain (UKHLS; Wave 8; 2016–2018) and Germany (SOEP, 2017). Sequence and cluster analyses detect patterns of dyadic employment biographies (ages 20–55) among different‐sex couples in their first marriage and OLS regressions associate them with the within‐couple gender wealth gap. Results The within‐couple gender wealth gap to the disadvantage of women existed in Britain and Western Germany, with considerably larger inequality in Germany. German male breadwinner couples, particularly those with longer periods of female homemaking and part‐time employment, showed higher levels of wealth inequality. Whereas dyadic employment biographies were not clearly associated with the gender wealth gap in Britain, stable arrangements of female full‐time employment reduced the gap in Germany. Conclusion A similar division of labor throughout the life course can result in different levels of the within‐couple gender wealth gap in later life across country contexts, particularly depending on the housing system.

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