A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a p -phenylazo bridge and the structural characterizations were achieved by FT IR, 1 H and 13 C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely Acinetobacter calcoaceticus (ATCC23055), Escherichia coli (ATCC2592), Pseudomonas aeruginosa (ATCC27853), and Staphylococcus aureus (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.
BACKGROUNDBalantidium coli is a ciliated protozoan that can infect various mammals, including pigs and humans. Human infection (balantidiasis) is brought feco-orally by consuming infective cysts with food and water. The trophozoites afterward mature and remain active in the intestinal lumen. Balantidiasis typically has no symptoms, but when it does, the manifestations include diarrhea, abdominal cramps, fever, nausea, and vomiting. More severe disease consequences and extraintestinal involvement often affect individuals with immune deficiency and underlying diseases. [1][2][3][4] Herein, we report a case of bladder cancer with B. coli in urine.
| CASE PRESENTATIONA 71-year-old Iranian woman was transferred to our center with fever, chills, and flank pain for a week. One year earlier, she underwent transurethral resection of the bladder (TURB) for a bladder lesion. The pathologic report declared invasive high-grade urothelial carcinoma, but she did not accept to do chemotherapy and surgery for cystectomy. After that, she was relatively well until 3 months ago when she presented with oliguria and abdominal pain. Sonography revealed severe bilateral hydronephrosis in addition to the advanced tumoral process in the pelvic cavity. Bilateral nephrostomy tubes were inserted, and she was discharged from the hospital. She had no
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