Obesity is a leading worldwide health threat with ever-growing prevalence, it promotes the incidence of various diseases, particularly cardiovascular disease, metabolic syndrome, diabetes, hypertension, and certain cancers. Traditional Chinese Medicine (TCM) has been used to control body weight and treat obesity for thousands of years, Chinese medicinal herbs provide a rich natural source of effective agents against obesity. However, some problems such as complex active ingredients, poor quality control, and unclear therapeutic mechanisms still need to be investigated and resolved. Prodrugs provide a path forward to overcome TCM deficiencies such as absorption, distribution, metabolism, excretion (ADME) properties, and toxicity. This article aimed to review the possible prodrugs from various medicinal plants that demonstrate beneficial effects on obesity and seek to offer insights on prodrug design as well as a solution to the global obesity issues.

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Chinese medicinal herbs (CMHs) have been used for thousands of years because of their significant properties regarding the prevention and treatment of diseases, such as COVID-19. There is an increasingly diminishing supply of wild medicinal resources, and the demand is greater than the supply. Ecological balance and the conservation of natural Chinese medicinal herbs are serious issues in sustainable development, which requires the minimum requirements to be met without compromising the resources of future generations, especially with respect to the maintenance of production and consumption as well as the quality control of CMHs. Hong Kong is an urban business city, busy with work and the fast pace of life. The sustainable development of CMHs is difficult in a huge population situated in an area with very scarce land coverage. The conservation of CMHs in urban horticulture is extremely neglected because people lack living space; for example, Aquilaria Sinensis (the incense tree), also called “pak muk heung” in Cantonese, was an indigenous species that was illegally logged in the past. This led to detrimental effects on the population density and genetic diversity of the species. There is no doubt that Hong Kong is required to set up a management model in community facilities for these emerging modern social configurations, such as building a Chinese herbal garden for the conservation and promotion of a healthy urban environment and giving people a chance to gain more information on CMHs. The current study employed problem analysis and strategic decisions for the sustainable development of 62 kinds of CMHs in a Chinese herbal garden, which converged with some medicinal itineraries of Lingnan herbal medications, and implemented a theoretical framework of management models for ten secondary schools, e.g., the Aroma garden of the L’Occitane at the Technological and Higher Education Institute of Hong Kong (THEi) Tsing Yi campus and Land from the Far East Consortium International Limited in Sai Kung Pak Kong. In the present original article, we would like to establish a sustainable management model for Chinese herbal gardens in an urban city. The sustainable development model for the Chinese herbal gardens is based on five major aspects: (1) land resources, (2) manpower planning, (3) economy, (4) education or training, and (5) ecosystem (cultivation). These are the essential factors of management and are implemented in our Chinese herbal gardens. We aim to find a suitable management model for Chinese herbal gardens and to promote it in other urban cities.

Letter to Editor titled "TaiChi" Exercise for Elderly Care