Background Work-related musculoskeletal disorders have been perceived as one of the reasons of declining work productivity in relation to absenteeism, sick leave or early retirement. We have determined the prevalence of musculoskeletal symptoms among current working civil servants and have assessed the health impact of musculoskeletal disorders towards them or other people surrounding them. Methods Participants were given a self-administered questionnaire consisting of demographic data, experience of musculoskeletal disorders, perceptions, knowledge and attitudes towards musculoskeletal disorders. Out of 174 participants, 147 returned completed forms (response rate: 84.5%). Data were analysed using SPSS Statistics v22. Results The average age of the respondents with standard deviation was 39.9 ± 9.82 years and a majority were female (78.2%). Mean body mass index between the participants were 26.36 ± 5.26, normal to obese range. Most of the participants described their type of job as active in nature (51.7%) with a majority working 5-8 hours per day. Mean duration for years of working in service were 16.20 ± 9.53. Half of them had musculoskeletal pain within the last 3 months prior to the study date, with highest frequency over the knee joint (29.9%) followed by lower back (21.8%) and shoulder area (21.1%). From the multivariate logistic regression analyses, only 2 factors in the knowledge section showed statistical associations regarding questions asking whether the participants knew what arthritis was (p = 0.005), and if they experienced arthritis themselves (p = 0.002). We found that there were no significant associations between the race, education level, marital status, type of work, duration of work or body mass index (BMI) with the prevalence of musculoskeletal pain within the participants. Conclusion The majority of respondents had knee pain followed by lower back pain and shoulder pain. Although there is strong correlation between knowledge of arthritis among participants, majority of them cannot specify the type of arthritis correctly. As such, continuous health education and promotion of the programme is vital. Disclosures H. Ariff None. N. Shahril None. L. Eow None. W. Wan Musa None. S. Rajalingam None. M. Jeffrizal None. A. Ramlan None. S. Selvadurai None. D. Ang None. D. Suahilai None. L. Mohd Isa None.

Background:Systemic lupus erythematosus (SLE) and Rheumatoid Arthritis (RA) often affects women in their reproductive years. These women are faced with a life-long illness that may have considerable impact not only on their physical health, but also on their reproductive potential. Fertility of these women may also be affected by the disease, treatment and/or organ damage.Objectives:To determine the role of infertility, pregnancy loss and childbearing decision and patients concerns on family size in women with SLE and RAMethods:A cross sectional study using a self-administered reproductive history questionnaire completed by woman with SLE/RA attending Rheumatology clinic follow up in Hospital Putrajaya, Hospital Tengku Ampuan Rahimah, and Hospital Raja Permaisuri Bainun, Malaysia from 1 January 2017 to 30 June 2017.Within each disease cohort, women were identified into 3 groups, those with fewer children than planned (group A), those with same number of planned children (group B) and those with completed family or not interested in having any children (group C). Data on number of children, pregnancies, misscariges and self reported infertility were recorded.For group A, data on patient concerns and the factors that could impact family building were also obtained.Results:Total of 110 women with SLE and 91 women with RA were surveyed. The mean age of women with SLE and RA were 37.6 years (+/- SD 7.4) and 45.37 years (+/- SD 11.7) respectively. Majority of women (48.8%) with SLE and RA were in group A with 59% (n=65) of women with SLE and 33% (n=33) of women with RA had fewer children than originally planned.The average numbers of pregnancies were similar in both cohorts, but women with SLE had 1 less child and were more likely to report infertility and had higher rate of miscarriages (Table 1). SLE group A had a similar number of pregnancies, but 1 less child compared to SLE group B and C (Table 2). Similarly, among women with RA, group A had 1 less child with similar number pregnancies and miscarriage rate (Table 2). In both groups of women, concerns about inability to care for a child, damage from medications, and genetic transmission of their disease were associated with a lower pregnancy rate.Table 1Number of pregnancies, live births, miscarriages and rate of infertility among women with SLE and RA* SLE RA P No. of pregnancies2.28 ±1.6262.60 ±1.9490.128No. of children1.85 ±1.2352.19 ±1.731 0.019 No. of miscarriages0.46 ±0.8090.36 ±0.659 0.040 No reporting infertility (%)5 (4.5)2 (2.2)0.366*values are the mean +/- SD unless otherwise indicatedTable 2Pregnancy outcomes for women with SLE (n=110) and RA (n=91) *Fewer children than desired(group A)Expected number of children(group B)completed family (group C) SLE RA SLE RA SLE RA No. of woman, n (%)65 (59.1)33 (36.3)20 (18.2)31 (34.1)25 (22.7)27 (29.7)No. of pregnancies2.11 ± 1.5922.03 ± 1.7232.3 ± 0.8652.81 ± 2.122.72 ± 2.0923.07 ±1.9No. of children1.57 ± 1.2121.55 ± 1.4162.1 ± 0.5532.39 ± 4.8562.36 ± 1.4972.74 ± 1.745No. of miscarriages0.51 ± 0.8310.36 ± 0....