The incidence of Cancer is still increasing worldwide, specially, at an alarming rate in the developing countries and remain one of the major cause of morality worldwide. The role of different antioxidants, both in fruits and vegetable and in synthetic form as chemo-preventive measure is now well established from different studies. The incidence of cancer is lower in those countries where the traditional diet provides plenty of antioxidants. The aim of this study is to evaluate standard modalities of patients with different neoplastic diseases. Three identically designed, open and multi-centric studies were conducted at the same time in Bangladesh in 2008-2009. Efficacy of antioxidant rich product, Oncoxin, in head and throat, breast and uterine cervix cancer, when administered with conventional oncologic therapy Each study included 30 patient couples with similar stages of cancer. One patient of each couple received the standard treatment for their stage (reference group). The other (experimental group) also received Oncoxin for 365 days. The result gathered in the 3 studies showed that the administration of Oncoxin led to a significant improvement of the quality of life of patients, fewer episodes of depression and increased optimism. These patients handled better the radiotherapy and chemotherapy sessions with fewer and less intense adverse reactions. During the final visit, it was observed a 59.26% increase in the Karnofsky index in the experimental group compared to 30.38% in the reference group, and a 16.05% drop (76.93% due to deaths) in the experimental group for 39.24% (64.52% due to deaths) in the reference group. Survival rates were greater in the experimental group in all three studies (87.65% versus 74.68%). The treatment with ONCOXIN Solution proves its effectiveness as a treatment modality associated with complex oncological treatment, the short and medium terms.TAJ 2009; 22(1): 172-175

Image guided FNAB of pulmonary lesions are widely applied now a days. Most of the lesions which are located nearer to the chest wall can be well visualized by ultrasonography. Whereas smaller lesions, deeply located ones, mediastinal or juxtra-hilar lesions may not be visualized sonographically. In those cases CT-guidance becomes beneficial. We report 127 FNABs done during a 2 year period. In considering the poor economic ability of the patient USG-guidance was preferred provided the lesion could be well visualized. Ultrasound guided method was successfully performed in majority of cases except a few where CT-guidance was necessary. After first aspiration an immediate cytological assessment was done by a quick staining method and in case of inadequacy of the specimen a second pass was made within an hour. Different pathological spectrum of diseases was diagnosed cytologically and was compared with their final diagnosis. Negligible immediate or late complications were noticed. Image guided FNAB of intra-thoracic masses can therefore be made with minimum complication, can allow the physician to decide the mode of treatment in a shortest possible time and in most of the cases an ultrasound guidance is sufficient enough to meet the poor economic status of people in this subcontinent. doi: 10.3329/taj.v20i2.3070 TAJ 2007; 20(2): 110-115

Image guided FNAC of pulmonary lesions are widely applied now a days. Most of the lesions which are located nearer to the chest wall can be well visualized by ultrasonography. Whereas smaller lesions, deeply located ones, mediastinal or juxtra-hilar lesions may not be visualized sonographically. In those cases CT-guidance becomes beneficial. We report 127 FNACs done during a 2 year period. In considering the poor economic ability of the patient USG-guidance was preferred provided the lesion could be well visualized. Ultrasound guided method was successfully performed in majority of cases except a few where CT-guidance was necessary. After first aspiration an immediate cytological assessment was done by a quick staining method and in case of inadequacy of the specimen a second pass was made within an hour. Different pathological spectrum of diseases were diagnosed cytologically and was compared with their final diagnosis. Negligible immediate or late complications were noticed. Image guided FNAB of intra-thoracic masses can therefore be made with minimum complication, can allow the physician to decide the mode of treatment in a shortest possible time and in most of the cases an ultrasound guidance is sufficient enough considering the poor economic status of people in this subcontinent.

Liver metastases are the leading cause of death in patients with colorectal cancer Despite advances in chemotherapy, surgical resection of hepatic metastases is still considered the only curative treatment the majority of patients have inoperable disease at presentation. Perioperative chemotherapy is the most successful way for improved selection of patients for resection. The aim of the study was to demonstrate if and to what extent does bevacizumab, introduced in chemotherapy, increase response rates, and development of liver metastases. Our study included 25 patients who were divided in two groups. The experimental group included patients who were treated with bevacizumab plus chemotherapy and the control group included patients who were treated with chemotherapy only. The comparison showed that the patients who were treated with bevacizumab became candidates for resection of liver metastases in higher percentage (85%:52%). On the otherhand distribution of patients regarding the development of metastases resulted in statistically significant difference. Ratio between the patients with good response from the experimental and the control group was 67%:39%. Ratio of patients with stable disease was 26%:48%, and of patients with progressive disease, it was 7%:3%. The estimate of margin after resection was statistically insignificant.TAJ 2011; 24(2): 101-105