Introdução: O câncer acometerá cerca de 50% dos indivíduos com infecção pelo vírus da imunodeficiência adquirida (HIV), com importante carga daqueles do tipo não definidores da síndrome da imunodeficiência adquirida (aids). Objetivo: Analisar diferentes fatores de risco para câncer do tipo não definidor na população HIV positiva, por meio da seleção de estudos de coorte realizados em diferentes Regiões do mundo. Método: Trata-se de uma revisão de literatura realizada no período de março a abril de 2019, utilizando os descritores Cancer Risck, HIV e non-AIDS-defining Cancer. Resultados: Os cânceres não definidores, que representam maior incidência entre a população HIV positiva, são o de pulmão, colorretal, cervical, de vagina e útero, gástrico, linfoma de Hodgkin e de fígado. Conclusão: Os estudos demonstram risco aumentado para diversos tipos de câncer não definidores da aids, o que nos leva a um novo paradigma, voltado não somente para o controle do HIV, mas também para a detecção precoce e tratamento oportuno, a fim de minimizar as morbidades e aumentar a expectativa de vida desses indivíduos.
Background: Individuals with Parkinson’s Disease present motor and cognitive impairment. In the language domain PD is a good model to study the functional contribution of the motor system to language processing. Objective: To investigate the performance of Parkinson’s disease patients on a lexical-semantic processing task of action verbs, compared to cognitively healthy controls. Methods: Parkinson’s patients performed the naming (n=25) and semantic association (n=19) tests of the Kisssing and Dancing Test - KDT, adapted by Baradel (2016). Patients were compared to cognitively healthy controls (n=44). Results: We observed a difference in performance on the naming (t[47]=-2.609, p=0.012) and semantic verb association (t[36]=-4.795, p=0.000) tasks between the groups. Parkinson’s patients had lower mean scores than healthy controls on both the naming and semantic association tasks. Conclusion: Parkinson’s patients may exhibit difficulties in lexical and semantic access of language with action content compared to healthy subjects. These results are consistent with Embodied Cognition and may support therapeutic alternatives in the field of language neuroscience.
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