Nosocomial infections are infections that develop after 48 hours of admission or within 30 days of discharge from a healthcare facility. The aim of the study was to investigate the rate of occurrence and types of nosocomial infections in patients admitted to the surgical wards. An audit based on records of patients who developed nosocomial infections was conducted. Data extracted included patients' demography, comorbidities, the organisms cultured, and their resistance patterns. A total of 574 records from 421 patients were found. Seventy percent (69.8%: 294/421) of the patients were males and 66.3% (279/431) were less than 51 years old. Ninety-four (22.3%: 94/421) patients were found to have polymicrobial infections. The records included 62 species of bacteria and 7 candida species. Around 74.7% (429/574) of the cultured organisms were ESKAPE pathogens. The most cultured organism was K. pneumoniae at 18.6% (107/574). Fifty-one percent of the cultured bacteria were resistant to antimicrobials. The overall rate of nosocomial infection was 8.7% with an incidence density of 468.20 per 100 000 patient days. Nosocomial infections were more prevalent in vascular, trauma and neurosurgery patients.