Effects of ratios of feldspar to CaCl2 to NaCl, roasting temperature ,roasting time and particle size on the melting-out rate of potassium from feldspar was studied by roasting. Results showed that the highest melting-out rate of potassium reached at 95.35% under the ratio of 1.8:1.1:0.6 of feldspar to CaCl2 to NaCl, particle size 220mesh, roasting temperature 800°C, roasting time 1h.

A stability-indicating reversed-phase high-performance liquid chromatography method has been developed and validated for the assay of indiquinoline tartrate and its related substances. The method was established by forced degradation experiments and system suitability experiments. The chromatographic separation was achieved with a Hedera ODS-3 column (5 µm, 250 mm × 4.6 mm) and the mobile phase was constituted (flow rate 1.0 mL/min) of eluant A, aqueous acetate buffer and eluant B, CH(3)OH using a gradient elution. A photodiode array detector set at 254 nm was used for detection. The investigated validation elements showed that the method has acceptable specificity, accuracy, linearity, precision, robustness and high sensitivity with limit of detection and limit of quantitation. The method can be used for routine quality control analysis and stability testing of indiquinoline tartrate drug substance.

The overlapped chromatograms and spectra of sulfadiazine (SD) and sulfamethoxazole (SM) in both synthetic samples and pharmaceutical tablets even in the presence of uncalibrated and interfering sulfanilamide (SN) were resolved by HPLC-DAD combined with a novel second-order calibration method. Their elution time was set from1.077 min to 1.624 min and the detection wavelength was chosen from 230 nm to 316 nm. The recoveries of SD and SM were (99.3 ± 1.3)% and (99.2 ± 3.1)%, respectively. The satisfying results show this method can be easily performed and applied to solving second-order calibration problems quickly and accurately.

Ten strains of silicate bacteria were screened from three bauxite samples in Jiangxi Province and Henan Province in China. The ten strains were determined as B. mucilaginosus according to the results of physiological and biochemical characteristics and desilicon ability. Bioleaching tests showed that the ten strains all can decompose bauxite ore and release silicon from bauxite, but had a large difference of desilicon ability among them.

The strain Jgj-1 was isolated from Gaoan bauxite ore. The relations of desilication of the strain Jgj-1 and the pH of solution, temperature, shaking speed, incubation time, particle size were investigated. The results shows the optimum conditions of bioleaching are as following: at 28°C, initial pH value is 7.2, particle size 0.056mm, 200rpm shaking speed, incubation 5-7 days.