This article presents an experience-based research effort on humansystems integration (HSI) verification principles for commercial space transportation (CST). CST HSI safety, efficiency, and comfort are analyzed with respect to four critical areas: (1) design and layout of displays and controls (we assume that displays and controls are computer based), (2) mission planning, (3) restraint and stowage, and (4) human factors in vehicle operations. HSI is analyzed using most recent approaches in human-centered design, which integrates technology, organization, and people from the very beginning of the design process and all along the life cycle of systems, including manufacturing, delivery, training, operations, and dismantling. CST HSI verification principles for the four critical areas are provided in the form of recommendations structured along with the five concepts of the AUTOS pyramid.

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