Background-To estimate the response rate and therapy related toxicities of the anti-CD20 monoclonal antibody rituximab when combined with chemotherapy including ifosfamide, carboplatin, and etoposide (ICE) in patients with relapsed and refractory B-cell non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia (B-ALL).

aRBCX may have increased complication risks compared with MET for chronic transfusion therapy in SCD. Risks and benefits of aRBCX and MET should be considered when selecting a chronic transfusion modality. Transfusion therapy modalities should be compared in prospective studies for stroke prevention in children with SCD.

This clinical practice guideline provides recommendations for preventing acute and delayed phase chemotherapy‐induced nausea and vomiting (CINV) in pediatric patients. The recommendations are based on two systematic reviews of randomized controlled trials evaluating interventions to prevent (1) acute phase CINV and (2) delayed phase CINV. Recommendations for acute phase and delayed phase CINV prophylaxis are made for patients receiving chemotherapy of varying emetogenicity, as well as for patients not able to receive dexamethasone or a neurokinin‐1 receptor antagonist. Evidence gaps, including antiemetic safety and optimal dosing, were identified.

These findings suggest an urgent need for multisectoral primary prevention of TBI, as well as culturally secure and logistically appropriate medical and rehabilitation service delivery models to optimize outcomes.

We describe a survey of the use and effectiveness of 12 manufacturing practices. The survey was administered to a random, stratified sample of companies with 150 or more employees in the United Kingdom, Australia, Japan, and Switzerland, yielding a total sample of 898 companies. We report findings on the extent of use of the practices, when they were introduced, their predicted future use, their effectiveness, and the correlates of their use and effectiveness. The data are examined for differences by country of location and country of ownership, as well as by industrial sector.