Huntington's disease (HD) is a fatal, inherited neurodegenerative disorder. The study in functioning and aging of neurons may give an opportunity to regulate these processes. Previous investigations demonstrated the ability of EDR peptide (Glu-Asp-Arg) to penetrate a cell nucleus and stimulate gene expression. The data obtained prompt EDR peptide capability to restore the morphology of spines in striatum neurons in Huntington's disease (HD) mouse model. EDR peptide has been shown by us to bind the DNA in solution (absorption spectroscopy and dynamic light scattering) and in a computer model. The proposed model suggests that EDR peptide binds specific binding site oligo (dCG) along the DNA minor groove.
This study observed the effectiveness of UC-MSC Stem Cells in alleviating Prader-Willi syndromes. One good reason was that UC-MSC with a wide variety of stem cells is well-sourced and easy to collect and preserve. It also has the capability of multi-directional differentiation. It can differentiate into bone, adipose, cartilage, and other tissues and meet this endeavor's intended purpose. Besides it, UC-MSC is also the product of Celltech Stem Cell Laboratory & Banking (CSC) where this study is initiated. Experiments were applied on patients of different sexes to see the results of the treatments where both meet satisfactory expectations.
The purpose of this case is to see the effects of mesenchymal umbilical cord treatments when applied to patients with Autism. The observations are of patients attending the main clinic, "Celltech Stem Cell and Banking," in Jakarta, Indonesia. Findings on pre-treatments showed abnormally varying behaviors, physically as well as psychologically. The treatments were conducted at the Celltech Stem Cell Lab clinics in Jakarta, based on good reasons that MCSUC are well-sourced, easy to collect and preserved, besides its traits of multi-directional differentiation. Patients undergoing the treatments showed calm and friendly behaviors and of the five cases presented, all fulfilled the pre-set standard criteria of recovery. This research has implications for paving the way for the development of innovative stem cell therapies for children with autism.
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