During the coronavirus disease global pandemic, urgent strategies to alleviate shortages are required. Evaluation of the feasibility, practicality, and value of drug conservation strategies and therapeutic alternatives requires a collaborative approach at the provincial level. The Ontario COVID-19 ICU Drug Task Force was directed to create recommendations suggesting drug conservation strategies and therapeutic alternatives for essential drugs at risk of shortage in the intensive care unit during the COVID-19 pandemic. Recommendations were rapidly developed using a modified Delphi method and evaluated on their ease of implementation, feasibility, and supportive evidence. This article describes the recommendations for drug conservation strategies and therapeutic alternatives for drugs at risk of shortage that are commonly used in the care of critically ill patients. Recommendations are identified as preferred and secondary ones that might be less desirable. Although the impetus for generating this document was the COVID-19 pandemic, recommendations should also be applicable for mitigating drug shortages outside of a pandemic. Proposed provincial strategies for drug conservation and therapeutic alternatives may not all be appropriate for every institution.Local implementation will require consultation from end-users and hospital administrators.

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Introduction: Abnormal uterine bleeding (AUB) is a the most common complaint in the gynecology out-patient department that affects significantly the patient’s personal life and it is also responsible for increasing morbidity in women. The histopathological diagnosis of abnormal uterine bleeding (AUB) shows spectrum of patterns and pathologist plays a vital role in the reporting of endometrium and differentiating non-neoplastic lesion from neoplastic lesions, early detection of precursor lesions and exclusion of malignancy. The aim of this study is to study the spectrum of endometrial patterns in women with AUB and to correlate with the different age groups. Materials and methods: The present study was undertaken in histopathology laboratory of Department of Pathology, GMERS medical college and hospital, sola, Ahmedabad for period of 12 months from June 2021 to May 2022. A histopathological study of total 100 cases of endometrial biopsies was done. Biopsies received in 10% formalin were processed and Haematoxylin and Eosin sections were studied. Result: We studied 100 endometrial samples. Age distribution varied from 20 years to 70 years, majority of patients were between 41 to 50years (35%).Menorrhagia was the most common presenting complain. Most common pattern of histopathology was proliferative endometrium (29%) followed by secretory endometrium (14%) and Disorderly proliferative endometrium (9%). Malignancy was detected in (2%) cases. Conclusion: AUB significantly affects the quality life of women and leads to anemia. Hence histopathological examination plays a critical role in early diagnosis of endometrial pathology and provide appropriate gynaecological management. Keywords: Abnormal Uterine Bleeding (AUB), Endometrial biopsy, Histopathological Examination

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This series of open educational videos provides an in depth overview of various surgical preparation procedures. These instructional videos could be of interest to various medical and health science trainees in a variety of fields such as nursing or medicine. All patients featured in this video series have signed consent and release forms authorizing the release of these educational videos.