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A BSTRACT Background: Systemic disorder like diabetes mellitus is on the rise in developing countries like India and in many parts of the world. Early diagnosis of this disease will help to prevent the complications due to uncontrolled diabetes mellitus. Dentist helps in the early diagnosis of this disease as patients manifest several oral manifestations. Aims and Objectives: The aim of this study was to study the cytological and cytomorphometric changes of exfoliated cells of oral mucosa in diabetic patients. Materials and Methods: Thirty diabetic patients and 15 healthy controls were included in the study. From the buccal mucosa, smears were collected and Papanicolaou stain was used for staining. Cytological and cytomorphometric study was carried out. The cell diameter and nuclear diameter were measured on these smears and were compared with the control group with the help of “unpaired Student t test.” Results: Buccal mucosa exfoliated cells’ mean nuclear diameter of diabetic group and control group was 11.198 and 9.494 µm, respectively and the difference was highly significant. Conclusion: Our study suggests significant cellular changes in the diabetic patients, which may aid us in early detection of diabetes.

Background: Oral cancer is one of the leading cause of death in Indian subcontinent. Early detection will definitely reduce its mortality rate. Aims and Objectives: To assess knowledge of undergraduate dental students about oral cancer. Methods: A cross-sectional, questionnaire with 10 questions related to basic aspects of oral cancer was designed and distributed to 100 undergraduate students from January 2015 to June 2015. The data was collected, tabulated and analyzed statistically for number and percentage using EPI-Info statistical software version 6. Results: Most of the students assessed were females making to 60% (60), while males were only 40% (40). 49 females and 32 males routinely check the oral mucosa completely. 56 females and 34 males ask the patients about their personal history like habits of tobacco and alcohol. Conclusion: Even though most of the students had adequate knowledge regarding basics of oral cancer, curriculum should be revised in such a way to enhance the knowledge of students about oral cancer.

Background: Mat cells play a crucial role in homeostasis and inflammation. Recently mast cells have been associated with numerous malignancies like oral squamous cell carcinoma (OSCC).Aims and Objectives: To compare mast cell density in normal mucosa and squamous cell carcinoma and to assess the role of mast cells in oral squamous cell carcinoma.Materials and Methods: Our retrospective study included 40 specimens, 10 well differentiated OSCC, 10 moderately differentiated OSCC, 10 poorly differentiated OSCC and 10 controls. Mast cell density was determined by toluidine blue staining. Statistical analysis was carried out using Statistical Package for Social Sciences (SPSS) 17.0 version (SPSS Inc., Chicago, IL, USA).Results: When compared with controls, mast cells count was a higher in OSCC groups which was a statistically significant (P < 0.001). Conclusion: Mast cells have a significant role in OSCC.

Oral Squamous cell carcinoma is the most common malignant neoplasm affecting oral cavity, generally seen in individuals over 50 years of age and rarely before 40 years of age. As OSCC is rare in younger group, it may be often misdiagnosed resulting in inappropriate treatment leading to poor survival rates. Here we report a case of OSCC of left lateral border of the tongue in a 38 year old male patient and also review its literature.