Background: Advanced maternal age, generally signify age after 35 years at the time of delivery. It is associated with decreased fertility and increased risk.Methods: This was a prospective study conducted in Kamla Raja Hospital, G.R. Medical College, Gwalior (M.P.) during the period of one year from July 2015 to June 2016. Pregnant women aged 35 years and older at the time of delivery were selected and analyzed for maternal and perinatal outcome.Results: A total no. of 288 elderly pregnant patients were selected for the study. Most of the cases were in the age group 35 to 39 years (89.93%). Multi gravida (71.8%) and grand multi para (22.22%) constituted the largest group. Most of the cases belong to lower socio-economic status (90%). Percentage of unbooked cases was 82.98%. The causes of delay in pregnancy were preference for male child (23.95%) and unwareness of contraception (21.52%). The incidence of diabetes mellitus and chronic hypertension were increased. Overall cesarean rate was increased (35%). Incidence of abortions 28(9.72%), preterm delivery 18(6.25%), oligohydramnios 18(6.25%), APH 18(6.25%) and PROM 17(5.90%), low birth weight baby 30(13.19%), NICU admission 20 (6.94%), IUGR 11(3.81%) all were high. The preference for male child 69(23.95%) and lack of awareness 62(21.52%) were two major reason for continuing pregnancies and deliveries till late age.Conclusions: The present study showed that pregnancy at advanced age is a higher risk pregnancy in term of increased maternal and perinatal morbidity and mortality.
INTRODUCTIONCervical cancer is the third largest cause of cancer mortality in India after cancers of the mouth and oropharynx, and oesophagus, accounting for nearly 10% of all cancer related deaths in the country. Among women, it is the leading cause of cancer mortality, accounting for 26% of all cancer deaths. According to International agency for research in cancer estimates, mortality from cervical cancer is expected to witness a 79% increase from 74,118 deaths in 2002 to 132,745 deaths by 2025. 1 It is estimated that in India, 1,26,000 new cases occur each year. 2 The incidence of cervical cancer has decreased by more than 50% in the past 30+ years, due to the increasing use of cervical cancer screening with cervical cytology. 3 The mainstay of cervical cancer screening has been the Papanicolaou test, also known as the Pap test or the Pap smear. It was developed by Dr. George Papanicolaou in the 1940s who discovered that precancerous and cancerous cells could be identified in cytologic samples from vaginal aspirates. 4 Unlike most other malignancies, cancer of cervix is readily preventable when effective programmes are conducted to detect and treat its precursor lesions. 2 This disease has a natural history where the malignant epithelial transformation evolves over many years from carcinoma-in-situ to frankly invasive lesions. The ABSTRACT Background: Cervical cancer is the third largest cause of cancer mortality in India after cancers of the mouth and oropharynx, and oesophagus, accounting for nearly 10% of all cancer related deaths in the country. Methods: The present study carried out 300 patients in Gajra Raja Medical College in the Department of Obstetrics and Gynaecology, OPD and indoor admitted patients from July 2016 to December. 2016. The selected patients were examined with care to note any cervical lesion, appearance of cervix, nature of any cervical/ vaginal discharge. Then a cervical scrape was taken with an Ayre's spatula and slide stained and then examined. Results: The maximum cases of HPV were seen in CIN, LSIL and HSIL. Maximum incidence of all cases was seen in the age group of 30-50 yrs. The women married before 18 years had the highest incidence of CIN and HPV infection. Majority of the cases of cervicitis were co-infected with H-Vaginalis and Trichomonas. Most women opted for a sterilization procedure rather than any other method of contraception. Use of no contraception puts these women at a high risk of acquiring HPV infection from infected partners. Conclusions: Occurrence of HPV infection declines with increasing grades. Most of the patients with HPV infection had presented with non-specific symptoms of discharge P/V or lower abdominal pain.
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