Introduction Molecular diagnostics for SARS-CoV-2 infection characteristically involves the sampling of the throat or nasopharyngeal swab (NPS). However, these procedures are invasive, require necessary skills for sample collection, cause patient discomfort, and are non-conducive for extensive scale testing. Saliva is increasingly being suggested as an alternate diagnostic sample in SARS‐CoV‐2 infection. Objectives This scoping review was done with the objective of exploring the evidence on the role of saliva as an alternate diagnostic sample in SARS‐CoV‐2 condition. Methods Thorough search of the literature in major databases was undertaken in June 2020 using free text and MESH terms, followed by PRISMA to identify 17 studies for data extraction. Results and conclusions Evidence was summarised for study characteristics, salivary sampling characteristics, viral load, and longevity of virus in saliva. The literature supports that saliva offers a simple sample collection method compared to technique-sensitive NPS and has the advantage of point-of-care testing for initial screening in community or hospital-based set-up. The additional highlights of this review are heterogeneity in the current literature and the gaps in methodology. Therefore, a robust study design to generate higher levels of evidence has been proposed.
The world-wide crisis of COVID-19 pandemic has disrupted daily lives, global economies, intra/inter-countries political outlook and educational systems. Schools and colleges in India and abroad are under lock-down to maximize social distancing and minimize the spread of infection amongst students and teaching staff. Health sciences related universities and researchers are forced to adopt non-contact teaching and research.Present article highlights the positive impact and opportunities provided by COVID-19 crisis to health care research and academic set-up. We have compiled ethical, effective and practical guidelines to mitigate the impact on health care related research and academic front during these pandemic times in an Indian perspective. These guidelines and management suggestions can be modified to suit region based cases and can be applied in global perspective also.The suggestions in the current article provide a working collaboration of students and teachers to effectively connect on virtual platforms to strengthen their research output, giving suggestions of data-sharing and rapid review of proposals by online review ethical boards. This time is proposed to be used for generating a positive impact on health and research sector to use each adversity as an opportunity.
Background: Azadirachta indica (neem), belongs to the family of Meliaceae plants, is found in the Indian subcontinent. The neem tree is colloquially referred to as the village pharmacy due to its array of biological properties. Every part of the neem tree like its bark, leaves, sap, fruit, seeds, and twigs find a multitude of uses. It is customary to use them for management of skin diseases and various other infections. The anticancer properties of neem have been studied in the past and these include its ability to modulate the tumour environment, increase the cytotoxic ability of host monocytes and suppress the proliferation of tumour cells. The present review was conducted with the objective of scrutinizing and assimilating data about the usefulness Azadirachta indica in oral cancer from all the previously done work. Material and methods: A planned review was conducted of all the studies that investigated the role of Azadirachta indica in oral cancer. Literature search was carried out using PubMed, Scopus and Google scholar databases. In addition to electronic searching, hand searching, cross referencing and various internet engines were also used to collect data. The articles were perused and articles not pertinent to our search were omitted. Results and conclusion: The anticancer properties of neem were evaluated and the active constituents of neem have been demonstrated to unequivocally have preventive and therapeutic potential against oral cancer. Although, greater exploration of the anticancer properties of neem are required in order to effectively integrate it into the routine management of oral cancer.
Introduction:In present-day times, freely available software allows dentists to tweak their digital records as never before. But, there is a fine line between acceptable enhancements and scientific delinquency.Aims and Objective:To manipulate digital images (used in forensic dentistry) of casts, lip prints, and bite marks in order to highlight tampering techniques and methods of detecting and preventing manipulation of digital images.Materials and Methods:Digital image records of forensic data (casts, lip prints, and bite marks photographed using Samsung Techwin L77 digital camera) were manipulated using freely available software.Results:Fake digital images can be created either by merging two or more digital images, or by altering an existing image.Discussion and Conclusion:Retouched digital images can be used for fraudulent purposes in forensic investigations. However, tools are available to detect such digital frauds, which are extremely difficult to assess visually. Thus, all digital content should mandatorily have attached metadata and preferably watermarking in order to avert their malicious re-use. Also, computer alertness, especially about imaging software's, should be promoted among forensic odontologists/dental professionals.
Solitary pigmented melanocytic intraoral lesions of the oral cavity are rare. Oral nevus is a congenital or acquired benign neoplasm. Oral compound nevus constitutes 5.9%-16.5% of all oral melanocytic nevi. The oral compound nevus is commonly seen on hard palate and buccal mucosa and rarely on other intraoral sites. The objective of this article is to present a rare case report of oral compound nevus in the retromolar pad region along with a review of literature. A 22 year old female reported with a solitary black pigmented papule at retromolar pad region which was surgically removed and microscopic investigation confirmed the diagnosis of oral compound nevus.
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