Neurocysticercosis (NCC) is an acquired parasitic infection of the central nervous system (CNS) in humans caused by encysted pork tapeworm larvae, namely Taenia solium. NCC has been discovered to be the most common etiology of focal seizure among the pediatric population. The severe CNS sequelae by NCC might cause to poor quality of life, eventually lead to sudden death. In this study, we report a case of NCC in a fifteen-year-old girl. Case illustration: a fifteen-year-old girl suddenly experienced a focal seizure of the right hand, along with a decreased of consciousness. The duration of the seizure was less than five minutes. It recurred for three times since ten hours before admission to hospital. She admitted that it was the first unprovoked seizure in her life. There was no record of fever and cough. She had a history of eating pork in the rural region of Sumba Island. Physical examination demonstrated GCS E3V4M5, normal findings of general and neurological status. Computed Tomography (CT) scan with contrast revealed a hypodense calcified lesion appended by a cyst with a dot sign, located at the grey-white matter junction at left parietal region. These findings supported colloidal vesicular stage of NCC. The diagnosis of this patient was neurocysticercosis. Therefore, she was given albendazole 400mg bid and valproic acid (15mg/kg/day) for a month, and intravenous dexamethasone (1mg/kg) with a maximum dose of 12 mg qid. After a month of treatment, she did not either have any seizure or other complaints. CT scan evaluation demonstrated a radiological improvement. Summary: NCC is identified as one of the commonest causes of epilepsy and seizure. The combination between antiparasitic with another supportive therapy gives comprehensive treatment of NCC.
Background: Bilateral congenital femoral agenesis is a rare congenital anomaly. To our knowledge, there have only been three examples of simple congenital abnormalities linked to the femoral facial syndrome. We present a straightforward case of bilateral femoral agenesis in a 3-month-old female infant who did not have femoral facial syndrome and whose mother did not have diabetes. Discussion: Bilateral femoral agenesis is a rare and unusual anomaly; only six cases have been reported. Other structural are often involved; these include the acetabulum, musculature, vessels, and ligaments of the knee, tibia, fibula, and foot. In our case, there are no other anomalies found. The majority of cases, however, are sporadic; therefore, the parents may be reassured that the risk of further offspring being affected is negligible. The classification by Aitken is widely used. This classification is based on the severity of the hip and femur radiographic findings Case Presentation: A 3-month-old female baby presents with a complaint of short stature. The baby was born full term spontaneous labor, 2570 grams vigorous and started to cry immediately after birth. The mother has no history of diabetes, cigarette smoking, and exposure to teratogens. The parents were not related by blood. X-ray examination showed bilateral agenesis of the femur, normal tibia and fibula, and proximal cruris in lateral acetabula. Conclusion: Bilateral congenital femoral agenesis is a rare congenital anomaly. Although frequently related to maternal diabetes mellitus, there is no recognized cause for most cases.
Latar belakang. Sepsis merupakan penyebab utama morbiditas dan mortalitas pada anak dengan penyakit kritis yang dirawat di unit perawatan intensif anak (UPIA). Pada 24 jam sepsis, terjadi penurunan kadar seng serum dan secara bersamaan terjadi peningkatan kadar interleukin-6 (IL-6) dan skor PELOD-2. Hasil sebaliknya terjadi pada 72 jam sepsis.Tujuan. Untuk membuktikan korelasi negatif antara kadar seng serum dengan IL-6 dan skor PELOD-2 pada sepsis.Metode. Penelitian dengan rancangan potong lintang dua kali pengukuran dari Januari - Desember 2019 di UPIA RSUP Sanglah Denpasar. Subjek penelitian adalah anak berusia 29 hari sampai 18 tahun dengan sepsis berdasarkan skor PELOD-2 > 7 menggunakan metode consecutive sampling. Uji korelasi Pearson untuk menilai korelasi bivariat dan uji multivariat menggunakan uji korelasi parsial.Hasil. Empatpuluh subjek memenuhi kriteria inklusi. Rerata kadar seng serum pada 24 dan 72 jam adalah 59,5 µg/dl versus 64,2 µg/dl. Median IL-6 pada 24 dan 72 jam adalah 8,6 pg/dL versus 4,4 pg/dL, rerata skor PELOD-2 24 dan 72 jam adalah 11,2 versus 11,0. Korelasi Pearson kadar seng serum dengan kadar IL-6 pada 24 dan 72 jam adalah r= -0,078, p= 0,632 versus r= -0,218, p= 0,178. Korelasi Pearson kadar seng serum dengan skor PELOD-2 pada 24 dan 72 jam adalah r= -0,513, p= 0,001 versus r= 0,242, p= 0,132. Analisis korelasi parsial kadar seng serum dengan PELOD-2 pada 24 jam adalah r= -0,493, p= 0,002.Kesimpulan. Terdapat korelasi negatif sedang bermakna pada 24 jam sepsis antara kadar seng serum dengan skor PELOD-2 setelah mengontrol variabel kendali.
Sleep disorders are collection of symptoms characterized by disruption of amount, quality, or time of sleep.Adolescent are high-risk group for sleep disorders. Sleep disorders among adolescent are affected by various factors such as extracurricular activities, watching television, using computer, using mobile phone and homework could delay sleeping time. This study aimed to find the prevalence and risk factors of sleep disorders among adolescent in Junior High School. It was a cross-sectional study among students in St. Joseph Junior High School, Denpasar aged 12-15 years old in August 2019, by using stratified purposive sampling. Data was collected by using Sleep Disturbance Scale for Children (SDSC) which was filled by parents and children. Chi-square test and logistic regression were used for statistical analysis. This study showed the prevalence of sleep disorders was 47.8%. Disturbance with initiating and maintaining sleep was the most common disorder, 22.8%. Watching television, using computers and playing telephone / gadgets were associated with increased sleep disturbance (p=0.02, PR 3.17, CI 95% 1.17-8.59), (p=0.02, PR 2.64 CI 95% 1.14-6.14), (p=0.02, PR 2.94, CI 95% 1.12-7.7), while extracurricular activities, nap habits, caffeine consumption were not risk factors, (p=0.07, PR 2.3, CI95% 0.94-5.95), (p=0.28, PR 1.57 CI 95% 0.68-3.58), (p=0,78, PR 0.89, CI 95% 0.38-2.03). The prevalence of sleep disorder among adolescent was considerably high. Risk factors of sleep disorder were watching television, using computer, and using mobile phone/gadget.
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