Introduction: Singleton Merten Syndrome is a rare disease characterized by the presence of the dental dysplasia phenotype, calcifications in the aorta, progressive wear and loss of bone protein (osteoporosis) in the hands and feet. Patients have muscle weakness, poor motor development, abnormal dentition, deformities of the feet and hands, and skin lesions. Objective: This report describes the maxillomandibular rehabilitation of a patient with Singleton Merten Syndrome and an allergic reaction to the acrylic resin through maxillary overdenture and mandibular partial removable denture. Case report: Female patient, 18 years old, with clinical characteristics of Singleton Merten Syndrome and allergic reaction to acrylic resin, with complaints of loss of function and esthetics due to the absence of several teeth, but with the presence of unerupted maxillary and mandibular tooth buds. Maxillary overdenture and mandibular removable partial denture were made of polyethylene. Conclusion: The rehabilitation treatment with maxillary overdenture and mandibular partial removable denture provided better facial muscle support, restoring masticatory function and facial esthetics. With this treatment, it was possible to reestablish patient's satisfaction and self-esteem due to the correct construction of the prostheses, and minimize hypersensitivity reactions in the oral mucosa, which allowed the use of these prostheses by the patient without any complications.

Singleton Merten Syndrome is a rare disease characterized by the presence of the dental dysplasia phenotype, calcifications in the aorta, progressive wear and loss of bone protein (osteoporosis) in the hands and feet. Patients have muscle weakness, poor motor development, abnormal dentition, deformities of the feet and hands, and skin lesions. Objective: This report describes the maxillomandibular rehabilitation of a patient with Singleton Merten Syndrome and an allergic reaction to the acrylic resin through maxillary overdenture and mandibular partial removable denture. Case report: Female patient, 18 years old, with clinical characteristics of Singleton Merten Syndrome and allergic reaction to acrylic resin, with complaints of loss of function and esthetics due to the absence of several teeth, but with the presence of unerupted maxillary and mandibular tooth buds. Maxillary overdenture and mandibular removable partial denture were made of polyethylene. Conclusion: The rehabilitation treatment with maxillary overdenture and mandibular partial removable denture provided better facial muscle support, restoring masticatory function and facial esthetics. With this treatment, it was possible to reestablish patient’s satisfaction and self-esteem due to the correct construction of the prostheses, and minimize hypersensitivity reactions in the oral mucosa, which allowed the use of these prostheses by the patient without any complications.