Baseline serum hematocrit varies substantially in the population. While additive genetic factors account for a large part of this variability, little is known about the genetic architecture underlying the trait. Because hematocrit levels vary with age, it is plausible that quantitative trait loci (QTL) that influence the phenotype also show an age-specific profile. To investigate this possibility, hematocrit was measured in three different age cohorts of mice (150, 450, and 750 days) of the C57BL/6J (B6) and the DBA2/J (D2) lineage. QTL were searched in the B6D2F(2) intercross and the BXD recombinant inbred (RI) strains. The effects of these QTL were explored across the different age groups. On the phenotypic level, baseline serum hematocrit declines with age in a sex-specific manner. In the B6D2F(2) intercross, suggestive QTL that influence the phenotype were located on Chromosomes (Chr) 1, 2, 7, 11, 13, and 16. With the exception of the QTL on Chr 2, all of these QTL exerted their largest effect at 750 days. The QTL on Chr 1, 2, 7, 11 and 16 were confirmed in the BXD RIs in a sex- and age-specific manner. Linkage analysis in the BXD RIs revealed an additional significant QTL on Chr 19. Baseline serum hematocrit is influenced by several QTL that appear to vary with the age and sex of the animal. These QTL primarily overlap with QTL that have been shown to regulate hematopoietic stem cell phenotypes.

professional experiences and research interests range from mechanical engineering facilities design to research that applied engineering and molecular biology approaches to the study of the skeletal response to mechanical loading. As a Mechanical Engineer, she worked on facility design projects involving mechanical systems that included heating, ventilation, air conditioning, and energy conservation systems, as well as R&D of air conditioning equipment for Navy ships. Additional research interests have included the investigation of relationships among components of the indoor environment, occupants, and energy usage. Specifically, the effects of the indoor environment on occupant health and well-being and in parallel, how socially-mediated energy-saving strategies can increase awareness of energy use and/or increase energy saving behaviors. Dr. Lang's current research interests focus on identifying, assessing, and developing key skills, knowledge, attitudes, and other intrinsic and extrinsic factors required for engineers to effectively lead others, particularly other engineers and across cultures. Mr Identifying Engineering Leadership Potential During the On-Campus Recruiting Process AbstractRecruiters' perspectives are important in determining how students should best convey their leadership skills during the recruitment process. Recruiters are responsible for evaluating and identifying talent appropriate for today's dynamic global environment. This study aims to understand, from the recruiters' perspective, the important engineering leadership behaviors an engineering student needs to communicate during the on-campus recruiting process. Additionally, the study identifies what undergraduate activities or programs recruiters' value in demonstrating important engineering leadership behaviors. The study uses a qualitative interview approach to generate themes of engineering leadership behaviors that recruiters seek to understand during the on-campus recruiting process as well as strategies recruiters use to identify engineering leadership potential.Recruiters were asked to complete a qualitative interview questionnaire during their participation in the 2015-2016 recruiting activities at a large public institution. Interview questions explored the strategies recruiters use to identify engineering leaders, what engineering leadership behaviors are important for students to communicate, and student experiences that alert a recruiter of engineering leadership potential. A list of themes was generated using the constant comparative method. Triangulation of data was achieved through an independent focus group consisting of experienced engineering recruiters to verify the themes identified in the qualitative questionnaire. Utilizing these steps provides a structure for precise and complete analysis of the data with validation through the triangulation process.Results from this study inform engineering leadership educators on how recruiters perceive students' leadership potential in the early-stages of their careers rel...

This article provides an overview of the formation of engineering leadership programs across North America. The article describes how programs, learning communities, and research influenced the engineering leadership field.

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Meg completed her PhD in Workforce Education at Penn State, where she focused on interpersonal behaviors and their impact on engineering leadership potential. Meg is a board certified coach with experience in developing students' leadership and professional competencies through teaching and one-on-one coaching. She is most interested in developing student knowledge of leadership to impact their successful transition to the workplace.