No abstract

The selective reduction of quinolin-2­(1H)-ones promoted by a SmI2/H2O/MeOH system is reported for the first time. The reaction is effectively carried out to afford 3,4-dihydroquinoline-2­(1H)-ones under mild conditions in a one-pot fashion with good to excellent yields.

The reduction of quinolin‐2(1H)‐ones to 1,2,3,4‐tetrahydroquinolines promoted by SmI2/ H2O/ Et3N is reported for the first time. This reaction involving the reduction of the amides proceeds through C−O bond cleavage. A new method for the synthesis of 1,2,3,4‐tetrahydroquinolines in mild conditions is developed.

The carbon–carbon double bond formation via neodymium-mediated Barbier-type reaction of ketones and allyl halides in the presence of diethyl phosphite is reported for the first time. The reaction is highly α-regioselective and was conveniently carried out under mild conditions in a one-pot fashion. From a synthetic point of view, a series of conjugated alkenes were obtained in moderate to good yields in this one-pot reaction with feasible reaction conditions.