This study provides evidence that even though not presenting the classic risk factors for CC, SLE patients, especially those exposed to long-term immunosuppression, have increased chances of presenting more premalignant lesions than the general population and they probably need to follow a more stringent CC prevention program.

No abstract

Objective: To analyze the cytological findings of CT-guided percutaneous fine-needle aspiration biopsies of the lung, to demonstrate the diagnostic feasibility of the method in the investigation of pulmonary lesions, and to determine the complications of the procedure, evaluating its safety. Methods: A retrospective analysis of 89 patients with various types of pulmonary lesions who underwent 97 procedures over a period of five years. The patients were divided into groups regarding the indication for the procedure: suspicion of primary lung cancer (stages IIIB or IV); suspicion of lung cancer (stages I, II, or IIIA) and clinical contraindications for surgery; suspicion of pulmonary metastasis from other organs; and pulmonary lesions with benign radiological aspect. All of the procedures were performed with 25-gauge needles and were guided by spiral CT. The final diagnosis was confirmed by surgical biopsy and clinical/oncological follow-up. For the analysis of complications, the total number of procedures was considered. Results: The main indication for the procedure was suspicion of advancedstage primary lung cancer. The accuracy of the method for malignant lesions was 91.5%. The lesion was confirmed as cancer in 73% of the patients. The major complication was pneumothorax (27.8%), which required chest tube drainage in 12.4% of the procedures. Conclusions: The principal indication for CT-guided fine-needle biopsy was suspicion of primary lung cancer in patients who were not surgical candidates. The procedure has high diagnostic feasibility for malignant pulmonary diseases. The most prevalent complication was pneumothorax. However, in most cases, chest tube drainage was unnecessary. No deaths were related to the procedure.Keywords: Biopsy, fine-needle; Tomography, spiral computed; Lung neoplasms; Pneumothorax. ResumoObjetivo: Analisar os resultados citológicos de biópsias aspirativas percutâneas por agulha fina guiada por TC de pulmão, demonstrar a viabilidade diagnóstica do método na investigação de lesões pulmonares e determinar as complicações do procedimento, avaliando sua segurança. Métodos: Análise retrospectiva com 89 pacientes com tipos diversos de lesões pulmonares que foram submetidos a 97 procedimentos em um período de cinco anos. Os pacientes foram divididos em grupos de acordo com a indicação para o procedimento: suspeita de neoplasia pulmonar primária (estádios IIIB e IV); suspeita de neoplasia pulmonar (estádios I, II e IIIA) e contraindicações clínicas para cirurgia; suspeita de metástase pulmonar oriunda de outros órgãos; e lesões pulmonares com aspecto radiológico benigno. O método foi padronizado com agulha fina de 25 gauge. Todos os procedimentos foram guiados por TC helicoidal. O diagnóstico final foi confirmado por biópsias cirúrgicas e acompanhamento clínico/ oncológico. Para a análise das complicações, foi considerado o número total de procedimentos. Resultados: A principal indicação do procedimento foi a suspeita de neoplasia pulmonar primária avançada. O método apresentou acuráci...

Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

Objectives. To assess the prevalence of self-medication in the urban adult population. Also to investigate the categories of medicines most used and its motivations. Method. The survey consisted of populational cross-sectional study, conducted between April and May 2010 at the Floriano city. The sample consisted of 552 individuals aged from 20 to 59 years. Results. The prevalence of self-medication considering the intire life of participants was 96.9%. In the last three months before the study, 37% have been self-medicated. The classes of drugs most commonly used were analgesics (34.2%), anti-inflammatory drugs (11%), sexual hormones (7.6%), antibiotics (6.5%) and vitamins (6.5%). The main reason for self-medication was pain (78.6%). Previous experience with the medication was the justification by 84% of the participants. Last year, 80.5% of participants who had any expenses with drugs admitted consuming drugs without prescription. Conclusions. This study showed high prevalence of self-medication in the adult population studied. Pain was the main reason for self-medication, which explains the consumption of analgesics by a majority of respondents. Previous experience with the medication was the main justification for self-medication. This demonstrates the need for preventive strategies in health in order to inform this population about the risks of self-medication and contributes to the rational use of drugs.