Objective. Epilepsy surgery can potentially cure drug‐resistant epilepsy, but careful presurgical evaluation is vital to select patients who will profit from such an intervention. Many epilepsy surgery programs offer extensive presurgical evaluation including several days of video‐EEG monitoring. Non‐lesional epilepsy cases are rare among epilepsy surgery patients. We set up a lesionorientated paediatric epilepsy surgery program for patients with clearly localized lesions with limited presurgical diagnostics, in particular, with a maximum of 48 hours of non‐invasive EEG monitoring that did not necessarily include ictal EEGs.Methods. We retrospectively evaluated the outcome of patients who were operated on within our epilepsy surgery program with respect to seizure freedom.Results. Fifty‐two children and adolescents with MRI lesions at a mean age of 8.27 ± 4.83 years (range: 0.17‐18.87) underwent a resective procedure. The most frequent surgery was a hemispherotomy. Overall seizure freedom was 81.8% after 12 months and 85.6% after a median observation period of 20.45 months. Seizure frequency was reduced >50% in all other patients. Preoperative recording of an ictal EEG on the side of surgery had no effect on postoperative seizure outcome (p= 0.697), nor did recording of epileptiform discharges on the ipsilateral (p= 0.538) and contralateral side (p= 0.147).Significance. Our findings highlight the high success rate using a lesionorientated epilepsy surgical approach with reduced presurgical video‐EEG monitoring in the paediatric epilepsy population. Our data show that it is possible to reduce the complex pre‐surgical work‐up for epilepsy in children and adolescents by asking the basic question: “Is there any reason why the lesion should not be resected”.
Oxygen saturation was not affected by mode of delivery, was independent of Apgar score, cord hemoglobin, cord pH, vital signs, and capillary refill time in the first few minutes of life, and did not reach 90% in the first 5 min of life in healthy full-term neonates.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.