In Indonesia, the prevalence of CSOM is relatively high with most disease occurring in rural areas. The high rates in rural Bali with early progression to tympanosclerosis suggest a significant burden of potentially vaccine preventable illness.

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Karsinoma nasofaring (KNF) adalah tumor ganas THTKL yang paling banyak dijumpai di Indonesia. Gejala dan tanda karsinoma nasofaring yang sering berupa benjolan di leher, obstruksi hidung, epistaksis dan diplopia.Penelitian ini bertujuan untuk mengetahui profil klinis karsinoma nasofaring di RSUP Dr.  Mohammad Hoesin Palembang tahun 2014-2015.Penelitian ini merupakan penelitian deskriptif berupa serial kasus dengan menggunakan data sekunder dari rekam medis pasien di RSUP Dr. Mohammad Hoesin Palembang. Sampel penelitian ini adalah semua rekam medik pasien karsinoma nasofaring di RSUP Dr.  Mohammad Hoesin Palembang tahun 2014-2015. Pada tahun 2014 terdapat sebanyak 60 kasus (16,85%)  dan pada tahun 2015 terdapat 50 kasus (14,53%) dari total pasien KNF yang datang ke RSMH. Pasien KNF paling banyak (30,91%) terdapat pada kelompok usia 46-55 tahun. Sebanyak 72,73% pasien KNF adalah laki-laki. Gejala  yang paling sering ditemui adalah hidung tersumbat (49,09%), benjolan di leher (43,64%), dan mimisan (36,36%). Sebanyak 81,82% kasus KNF adalah KNF WHO III, selebihnya adalah KNF WHO II (15,45%) KNF WHO I (2,73%). Mayoritas kasus KNF adalah KNF stadium IV (77,27%). Pasien KNF paling banyak terdapat pada kelompok usia 46-55 tahun. KNF lebih sering terjadi pada laki-laki daripada perempuan. Gejala klinik yang paling sering ditemui adalah hidung tersumbat, benjolan di leher dan mimisan. Mayoritas gambaran histopatologi KNF adalah KNF WHO III. Sebagian besar penderita KNF didiagnosis sebagai KNF stadium IV.

Introduction Nasopharyngeal carcinoma is a malignant tumor that grows in nasopharyngeal area with a predilection in fossa of Rossenmuller and roof of nasopharynx. Nasopharyngeal carcinoma is the most common malignant tumor in the neck and head area. This research is to determine the characteristics of nasopharyngeal carcinoma at Moehammad Hoesin General Hospital Palembang. Methods This study design is restrospective descriptive and took the sample from medical records in department of ORL-HNS Moehammad Hoesin General Hospital Palembang between January 2013 until December 2017. Results In this study, the number of nasopharyngeal carcinoma patients January 2013 to December 2017 was 284 patient. Most of them were male (72.86%). The age of most patients ranges from 41-50 years (33.20%). The highest histopathological description of patients was WHO 2B (54.9%). Most patients were T4 (36.29%). Most patients nodules were N3 (34.09%). As many as 93.88% of patients have not experienced distant metastasis. Most patients came to the department of ORL-HNS had already been in stage IV (63.84%). The most chemotherapy regimens given were carboplatin and docetaxel. Conclusions Nasopharyngeal carcinoma is still a problem in many countries. The main management is radiotherapy with or without chemotherapy.

Thyroid nodules are a common clinical problem. The prevalence of palpable thyroid nodules approximately 5% in women and 1% in men. In contrast, high-resolution ultrasound (US) can detect thyroid nodules in 19-68%. The clinical importance of thyroid nodules is to exclude thyroid cancer, which occurs in 7-15% of cases depending on age, sex, radiation exposure, and family history. Incidental thyroid nodules are being diagnosed with increasing frequency in recent years with the use of newer and highly sensitive imaging techniques. The high prevalence of thyroid nodules necessitates that clinician use evidence-based approaches for their assessment and management. e revised guidelines for the management of thyroid nodules include recommendations regarding initial evaluation, clinical and ultrasound criteria for fine-needle aspiration biopsy, interpretation of fine-needle aspiration biopsy results, use of molecular markers, and management of benign thyroid nodules. Many nodules will not require biopsy. These nodules and those that are cytologically benign can be managed with long-term follow-up alone. If malignancy is suspected, options include surgery. When there are multiple options for diagnosis and/or treatment, they should be discussed with patients as frankly as possible to identify an approach that best meets their needs. This case discusses how to diagnose and treat thyroid-adenomatoid cyst thyroid nodules case with extirpation and thyroidectomy surgery so that the selection of management becomes more precise and can reduce the recurrence rate.