1. AIMS AND OBJECTIVES : Ÿ To determine the correlation between and predict the molecular subtypes of breast carcinoma based on mammography and ultrasound ndings. Ÿ To correlate the different epidemiological features of breast cancer patients with the molecular subtypes of breast carcinoma. 2. Materials And Methods: In our cross-sectional study, 84 biopsy proven cases of breast carcinoma were referred to radiology department. After taking informed consent and in presence of a female attendant, ultrasonography and mammography of the patients were done. All these patients went for surgical excision of the neoplastic mass; and the mass were sent for IHC analysis. Epidemiological data, clinical features, mammographic features and sonographic features were correlated with IHC subtype of the mass and P-Values were found out. P-Value<0.05 was considered to be statistically signicant. 3. Results: Ÿ Among 84 patients, 22 were of Triple Basal Negative subtype, 17 were of Luminal-A subtype, 16 were of Luminal-B (Her-2 negative) subtype, 15 were of Her-2 enriched subtype and 14 out of 84 patients were of Luminal-B (Her-2 positive) subtype. Ÿ IHC correlation between sex distribution, age distribution, age of menarche distribution, achievement of menopause and age of menopause distribution, parity distribution, history of breast feeding, family history of breast carcinoma, history of breast pain, breast ulceration, nipple discharge, quadrant location of breast mass and size of mass showed P-Value >0.05; which was statistically insignicant. Ÿ IHC corelation with mammographic microcalcications, shape of breast mass, margins of breast mass, posterior acoustic pattern of breast masses and vascularity of the breast mass showed P-Value <0.05; which was statistically signicant. 4. Conclusion: Mammographic microcalcication and other features on sonography like shape of the mass, margins of the mass, posterior acoustic features and vascularity of the mass are strongly correlated in predicting the molecular subtype of breast carcinoma.
Bowel injury secondary to blunt trauma abdomen is a commonly encountered entity. However, small bowel obstruction secondary to traumatic incarceration of bowel loops between two translated vertebras in a case of road traffic accident is seldom reported. We report a case of small bowel obstruction in a patient who had suffered spondyloptosis at the L1–L2 level after a motor vehicle accident. We also discuss the diagnostic work up and interventions done to manage the patient. The report also reviews pertinent published literature on the incarceration of the bowel associated with vertebral fractures.
Introduction: Placenta accreta (PA) includes various types of abnormal placentation in which chorionic villi attach directly to or invade he myometrium. There is a rising trend of placenta accreta owing to increased number of primary and repeat Caesarean sections. Accurate and timely identification of affected pregnancies allows optimal obstetric management to reduce maternal morbidity and mortality. The availability of conservative treatment modalities for the management of post partum hemorrhage arising from the same mandates the use of magnetic resonance imaging (MRI) to precisely evaluate the degree of placental invasion so as to further guide the treatment options. Materials and Methods: In two years observational cross sectional study, 18 pregnant females between age group 15-40 years were subjected to MRI pelvis and MRI findings were noted. Result : Placenta accrete vera was the most common type found in our study. Patients with placenta previa and previous Caesarean section were at highest risk. Intraplacental bands, heterogenous placenta, lumpy placental contour were the most commonly observed findings. Conclusion: MRI is very useful for accurate evaluation of placenta accreta particularly when USG findings are ambiguous or when there is a posterior placenta. There is increased incidence of placenta accreta with multiparity, placenta previa and history of previous Caesarean sections.
Introduction: Ultrasound (US) elastography is an emerging technique that can be used during breast US examination. Guidelines recommend mammographic screening and US for diagnosis of breast cancer. The specificity of these techniques is not high enough to prevent unnecessary biopsies. Hence there is need for a more specific technique to overcome this problem. This study aimed to evaluate the value of strain elastography (SE) for breast lesions. Materials and Methods: In this cross sectional observational study over 18 months, 60 women with palpable breast lumps were evaluated with conventional US and SE. Results obtained were correlated with histopathological findings for statistical analysis. Result: A statistically significant correlation was found between SE and histopathological outcome with a p value of 0.03(<0.05). The positive predictive value (PPV) was 76.92% and the negative predictive value (NPV) was 76.47% with Chi square= 8.4. Conclusion: Ultrasound with SE can substantially improve the possibility of differentiating benign from malignant breast lesions thereby limiting recourse to biopsy and considerably reducing the number of benign breast biopsy diagnoses.
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