laç reaksiyonları; herhangi bir hastalığın önlenmesi, tedavisi veya teş-hisi için uygulanan ilacın neden olduğu zararlı veya istenmeyen etkilerdir. Hemen her klinikte görülen ilaç reaksiyonları, tüm hastaların were women and 47 were men. The ages of the patients ranged between 55 and 85 years (mean age 63.8±8.4). The most frequently detected cutaneous drug reactions were urticaria, angioedema, maculopapular drug eruptions, fixed drug eruptions and pruritus. Anti-inflammatory agents, analgesics and antipyretics, antihypertensives, antimicrobials and neuropsychiatric drugs were the most commonly implicated drugs. A history of chronic disease and continuous drug use was evident in 60.4% of patients. Antihypertensives were the most frequent agents causing cutaneous drug eruptions. A history of drug allergy was present in 15.3% of the cases. C Co on nc cl lu us si io on n: : Anti-inflammatory agents, analgesics, antipyretics, antihypertensives and antimicrobial drugs lead to cutaneous drug reactions most frequently in advanced ages. Urticaria, angioedema and maculopapular eruptions are the most common clinical forms. Antibiotics and chemotherapeutics were determined to cause severe cutaneous reactions such as generalized exanthematous pustulosis and erythroderma.