Over the past several decades, the design and development of nanomaterials with intrinsic enzyme-mimicking activities (nanozymes) have attracted increasing attention. Herein, we present a simple strategy for the construction of graphene−gold nanoparticle (Graphene/Au-NPs) nanozymes via a one-step hydrothermal reaction, which can act as a highly efficient dye scavenger with the synergetic effect of adsorption and degradation. The asprepared nanocomposites can overcome the intrinsic drawbacks of singlecomponent Au-NPs, such as ease of aggregation and cannot capture substrates effectively. In our catalytic system, Graphene/Au-NPs can readily adsorb organic dyes onto their surfaces, catalyze H 2 O 2 to generate • OH radicals, and then exhibit outstanding removal performance toward different organic dyes. Their catalytic mechanism is analogous to that of natural enzymes, in which the specific high catalytic efficiency depends mainly on their capacity to keep the substrate close to the active site of the enzyme. Collectively, our work may pave the way to apply multifunctional nanozymes in different research areas, such as environmental treatment, sensing, and biotechnology.

Due to their excellent hydrophilicity, outstanding conductivity, unique structures, and physicochemical properties, MXenes have become a potential candidate material for flexible and wearable chemo- and bio-sensors.

With the rapid development of biology and nanotechnology, designing nanomaterials with intrinsic enzyme-like activities has huge attention in recent years. Herein, for the first time, we use zein as a...

BackgroundNonalcoholic Fatty Liver Disease(NAFLD)refers to a spectrum of diseases ranging from simple liver steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis. Bidirectional cross-talk between the gut-liver axis plays an important role in the pathogenesis of NAFLD. To learn more about the gut-liver axis in NAFLD, this study aims to provide a comprehensive analysis from a bibliometric perspective.MethodLiterature related to the gut-liver axis in NAFLD from 1989 to 2022 was extracted from the Web of Science Core Collection. Based on Microsoft Excel, CiteSpace and Vosviewer, we conducted to analyze the number of publications, countries/regions, institutions, authors, journals, references, and keywords.ResultsA total of 1,891 literature since 2004 was included, with the rapid growth of the number of papers on the gut-liver axis in NAFLD annually. These publications were mainly from 66 countries and 442 institutions. Of the 638 authors analyzed, Bernd Schnabl was the one with the most publications, and Patrice D. Cani was the one with the most co-citations. International Journal of Molecular Sciences is the journal with the most articles published, and Hepatology is the journal with the most citations. The most common keywords are gut microbiota, inflammation, and insulin instance, which are current research hotspots. Short-chain fatty acid, in vitro, randomized controlled trial in clinical, and diabetes mellitus represent the research frontiers in this field and are in a stage of rapid development.ConclusionThis is the first study to conduct a comprehensive bibliometric analysis of publications related to the gut-liver axis in NAFLD. This study reveals that gut microbiota, inflammation, insulin resistance, short-chain fatty acids, and randomized controlled trial will be the hotspots and new trends in the gut-liver axis in NAFLD research, which could provide researchers with key research information in this field and is helpful for further exploration of new research directions.

Hydrogels are an important class of soft materials with elastic and intelligent properties. Nevertheless, these traditional hydrogels usually possess poor mechanical properties and limited functions, which greatly restrict their further...