Purpose To establish a normative database and optimise parameters for personal-computer based perimetry via a web-application using circular contrast targets. Methods Online 24-degree 52-loci perimetry was delivered through a web-application using circular flickering contrast targets. Embedding contrast differentials within targets allows calculation of relative decibel (rdB) per 256-bit greyscale level differential. Target light-band maximum brightness colour was fixed, while the dark-band varied to achieve the desired rdB level. A staircase system was used with two reversals ranging from 0 to 36 rdB levels. Blind spot localisation at the start of the test was used to optimise viewing distance and subsequently count fixation losses. Gaze was maintained on a spinning golden star which moves mid-test to maximise sampling area. Patients performed the test to each eye separately using a computer in a darkened room at 40–45 cm. Results 158 eyes of 101 patients completed the Online Circular Contrast Perimetry (OCCP) test. Mean age was 62.9 ± 14.3 years old. Mean sensitivity reduced with age, at 1.0 relative decibel per decade. Mean sensitivity per locus correlated with standard automated perimetry (SAP) in a physiological hill of vision, with an average difference of 4.02 decibels (95% confidence interval (CI) = 3.77–4.27, p < 0.001) and good agreement between tests. Conclusions Online circular contract perimetry provides accurate perimetric testing with comparable results to standard automated perimetry.

Purpose: The aim was to validate and compare the diagnostic accuracy of a novel 24-degree, 52-loci online circular contrast perimetry (OCCP) application to standard automated perimetry (SAP). Design: Prospective cohort study. Methods: Two hundred and twenty participants (125 normal controls, 95 open angle glaucoma patients) were included. Agreement, correlation, sensitivity, specificity, and area under receiver operating curves (AUC) were compared for parameters of OCCP, SAP, and optical coherence tomography (OCT) for the retinal nerve fiber layer and macular ganglion cell complex inner plexiform layer. Results: Pointwise sensitivity for OCCP was greater than SAP by 1.02 log units (95% CI: 0.95–1.08); 95% limits of agreement 0.860 to 1.17. Correlation and agreement for global indices and regional zones between OCCP and SAP were strong. OCCP mean deviation (MD) AUC was 0.885±0.08, similar to other instruments’ parameters with the highest AUC: SAP MD (0.851±0.08), OCT retinal nerve fiber layer inferior thickness (0.908±0.07), OCT ganglion cell complex inner plexiform layer inferior thickness (0.849±0.08), P>0.05. At best cutoff, OCCP MD sensitivity/specificity were comparable to SAP MD (90/74 vs 94/65%). Conclusions: OCCP demonstrates similar perimetric sensitivities to SAP and similar AUC to SAP and OCT in distinguishing glaucoma patients from controls. OCCP holds promise as a glaucoma surveillance and screening tool, with the potential to be utilized for in-clinic and at-home perimetry and expand community testing.

Précis: Overall, 63% of glaucoma patients agreed to 45-60 minutes of daily meditation. Predictors of accepting meditation included previous meditation practice, a diagnosis of glaucoma <1 year, and having a marital status of “single”. Purpose: To explore patients’ acceptance and barriers towards 45-60 minutes daily meditation for glaucoma management and to identify glaucoma patients with higher perceived stress levels who may benefit more from meditation practice. Methods: Glaucoma patients attending the Royal Victorian Eye and Ear Hospital, Melbourne, Australia outpatient department were invited to complete a patient survey. This survey explored if patients would agree to 45-60 minutes of daily meditation and included the Determinants of Meditation Practice Inventory and Perceived Stress Scale questionnaires. Questionnaire scores were compared across participants’ clinical and demographic characteristics using Student t test, ANOVA, and multiple-linear-regression analysis. Results: Of the 123 eligible patients screened, 100 completed the survey (81.3%). Sixty-three (63%) patients would agree to 45-60 minutes of daily meditation if advised by their doctor. Univariate analysis showed increased acceptance of meditation (lower Determinants of Meditation Practice Inventory scores) to be associated with agreeing to meditate 45-60 minutes daily (P=0.002), currently or previously practicing meditation (P=0.006 and P=0.0004 respectively), and having a marital status as “single” (P=0.02). Multivariate regression analysis showed previous meditation practice and a glaucoma diagnosis of <1 year to be predictive of accepting meditation (P=0.01 and P=0.03 respectively). There were no predictive factors of Perceived Stress Scale scores. Conclusion: Given the high acceptance rate of 45-60 minutes daily meditation (63% of glaucoma patients sampled), this may be recommended for the benefit of patients. Patients who have previously meditated, have a relatively new diagnosis of glaucoma, and are single (marital status) were more accepting of meditation practice.

No abstract