Purpose The demand for energy is increasing massively due to urbanization and industrialization. Due to the massive usage of diesel engines in the transportation sector, global warming is increasing rapidly. The purpose of this paper is to use hydrogen as the potential alternative for diesel engine. Design/methodology/approach A series of tests conducted in the twin cylinder four stroke diesel engine at various engine speeds. In addition to the hydrogen, the ultrasonication is applied to add the nanoparticles to the neat diesel. The role of nanoparticles on engine performance is effective owing to its physicochemical properties. Here, neat diesel mixed 30% of biodiesel along with the hydrogen at the concentration of 10%, 20% and 30% and 50 ppm of graphite oxide to form the blends DNH10, DNH20 and DNH30. Findings Inclusion of both hydrogen and nanoparticles increases the brake power and brake thermal efficiency (BTE) of the engine with relatively less fuel consumption. Compared to all blends, the maximum BTE of 33.3% has been reported by 30% hydrogen-based fuel. On the contrary, the production of the pollutants also reduces as the hydrogen concentration increases. Originality/value Majority of the pollutants such as carbon monoxide, carbon dioxide and hydrocarbon were dropped massively compared to diesel. On the contrary, there is no reduction in nitrogen of oxides (NOx). Highest production of NOx was witnessed for 30% hydrogen fuel due to the premixed combustion phase and cylinder temperatures.