Aim The aim of the present study was to assess the role of hemoglobin A1c (HbA1c) in screening of gestational diabetes mellitus (GDM) and to compare its efficacy with 75 g oral glucose tolerance test (OGTT) (World Health Organization [WHO]) screening criteria. Methods A prospective observational study was performed on a total of 260 women attending antenatal outpatient department of our hospital at 24–28 weeks of gestation. All women underwent 75‐g OGTT testing, and WHO 1999 criteria was used for diagnosis of GDM. Also, a HbA1c test was performed for the same women. Results Prevalence of GDM was found to be 19.6% by OGTT. Mean HbA1c values in GDM was significantly higher than non‐GDM. HbA1c correlated well with both fasting and 2 h postprandial levels but there was better correlation with 2‐h postprandial level. Conclusion The incidence of gestational diabetes is rising in South‐East Asian countries, especially in India. HBA1c could be a potential screening test for GDM.

: Histiocytes with coffee bean like nucleus are the diagnostic hallmark of Langerhans cell histiocytosis (LCH) supported with immunohistochemical (IHC) demonstration of fascin, CD1a and S-100. We report a case of Letterer-Siwe disease in a 40year male diagnosed on cytology and IHC on cytosmears along with cytomorphology in Liquid based cytology (LBC) smears. Forty year male presented with complains of low grade fever and reduced appetite from two years with a cervical swelling and discomfort from five months. Fine needle aspiration(FNA) from cervical lymph node showed sheets of histiocytes in background of mixed inflammatory cells. LBC smears highlighted fine chromatin, delicate nuclear outline with coffee bean like morphology. On IHC tumor cells were positive for S-100 and CD1a. CT thorax revealed consolidation in left lower lung, bone lesions were found on skeletal survey. Hence diagnosis of Letterer-Siwe disease was given. Patient responded well to systemic chemotherapy.