Out of a total of 50 study-eligible patients, 15 patients were found to have synchronous breast cancer and gallbladder diseases. Fourteen such patients had breast cancer and cholelithiasis while 1 patient had breast cancer with gallbladder cancer. Amongst these 15 patients, 7 patients tested positive for chromosomal aberrations on karyotyping. Aberrations in these patients were seen on chromosomes 13 and 17 with 2 patients having deletion 13q, 2 having deletion 17q, and 2 having deletions on 17p while one patient had multiple deletions on chromosomes 13q and 17p. The patient with multiple aberrations on 13q and 17p had a grade III infiltrating ductal carcinoma (NOS) of the breast with adenocarcinoma of the gallbladder. On the basis of our study and its analysis, we conclude that synchronous breast and gallbladder lesions are common amongst females and the occurrence of one should warn the clinician to search for the other. Also, chromosomal aberrations are common amongst patients with synchronous diseases and since these abnormalities are in the germ line cells, genetic counselling should be offered to the first- and second-degree female relatives.

The Breast Conservative Therapy is the standard treatment for early-stage breast cancer in the western world. On the other hand, in India BCT is not preferred by the surgeons and patients (11-23% vs. >60-70%). Patients suffer from cancer, its treatments and the sideeffects of treatment. The majority of them encounter breast cancer multiplicity of physical and psychological difficulties after finishing cancer treatment. Without rehabilitation these difficulties may lead to functional limitations, disabilities, and mental issues. The breast cancer survival rate has increased, due to improvements in early diagnostic procedures and more aggressive therapies. Because of increased survival rate need of rehabilitation has been increased. The study was conducted with the aim of being able to determine the need of rehabilitation in patients of breast cancer after MRM in alleviating the disability also, to assess post MRM complication and to assess the psychological impairment and quality of life of breast cancer survivors.it was observed that out of 90/122 (73.77%) individuals were scoring below 40 which was suggestive of poor quality of life also, out of 122 patients 18 patients developed lymphedema. Amongst the 122 patients 54.97% wanted breast reconstruction & most of them belong to younger age group.

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Congenital diaphragmatic hernias occur in 1 in 3500 live births. Among the congenital diaphragmatic hernias, morgagni hernias are the rarest accounting for 2-3% of all diaphragmatic hernias. They occur through a congenital defect in the anterior part of the diaphragm just behind the sternum. In most cases the defect in the diaphragm is small and the patient may remain asymptomatic. The occurrence of obstruction or strangulation in these hernias is a rare occurrence. We report a rare case of right sided Morgagni hernia in a 14 years old boy who presented with features of subacute intestinal obstruction. Chest X-ray showed a large right sided diaphragmatic hernia with stomach and bowel loops compressing the right lung. A contrast enhanced computed tomography (CT) scan indicated large right sided diaphragmatic hernia containing gastric volvulus with twisted small bowel loops causing right lung collapse, and congenital anomalies of the right kidney and liver. The patient underwent exploratory laparotomy with an upper midline incision with reduction of hernia and primary repair of the diaphragmatic defect found in the anterior aspect of right diaphragm without placement of a mesh. An ICD was placed in right thoracic cavity to allow the lung to expand. Due to inadequate lung expansion a second ICD was placed in the right third intercostal space on the 9th post-operative day and removed on the 18th post-operative day. Patient was discharged with a single ICD on 20th post-operative day which was removed on first follow up. Patient was asymptomatic and recovered well subsequently.