Acute renal failure is an unusual complication of wasp stings. We report three cases who developed acute renal failure after multiple wasp stings (Vespa magnifica). Two patients had evidence of intravascular haemolysis and rhabdomyolysis whereas one patient investigation showed no evidence of intravascular haemolysis or rhabdomyolysis. All three cases had impaired liver functions. Oligo-anuria was seen in all three of the patients and all of them required dialytic support. One patient died of massive gastrointestinal bleeding while the remaining two recovered completely. Although acute renal failure after wasp stings is typically caused by acute tubular necrosis in the setting of haemolysis or rhabdomyolysis, in some patients, renal failure may result from a direct nephrotoxic effect or acute interstitial nephritis from a hypersensitivity reaction to the wasp venom.

Subcutaneous emphysema is a common condition occurring after chest injury. It may also be observed in association with pneumothorax or pneumomediastinum as a result of pathological changes in the respiratory tract. Spontaneous subcutaneous emphysema in absence of pneumothorax or pneumomediastinum is rare. We report a case of spontaneous subcutaneous emphysema in isolation secondary to fibrocavitatory lesion in the chest along with review of the literature.

We report a 22-year-old male patient with untreated seizure disorder, presenting with increased frequency of seizures followed by encephalopathy. Laboratory evaluation showed severe hypernatremia (175 meq/l sodium), rhabdomyolysis, and acute renal failure (ARF). Excessive insensible water loss in hot and humid weather, associated with an inability to obtain adequate water replacement, led to a hyperosmolar state (plasma osmolality, 398 mOsm/kg). He was vigorously treated with hypotonic fluid supplement and, further, needed dialysis therapy (peritoneal dialysis followed by hemodialysis) for acute renal insufficiency. The patient survived without any neurological sequelae, but the clinical course was complicated by acute deep vein thrombosis. This case represents what we believe is a unique report in the literature of severe hypernatremia developing via the pathogenic mechanism outlined above and the complication of acute peripheral venous thrombosis, which has not been reported in adults. The purpose of this report is to emphasize hyperosmolarity as a newly described cause of rhabdomyolysis, ARF, and a hypercoagulable state.

Infark ventrikel kanan yang terutama terjadi sebagai komplikasi infark inferior merupakan entitas penyakit tersendiri dimana dapat terjadi gangguan hemodinamik mayor. Pemeriksaan hemodinamik, elektrokardiografi (EKG), radionuklid angiografi dan ekokardiografi digunakan untuk mengetahui keterlibatan ventrikel kanan pada infark inferior. Infark ventrikel kanan terjadi pada 30 sampai 50% kasus infark inferior. Kami telah melakukan penelitian pada 37 pasien dengan infark inferior akut (dengan metode non invasif) dengan tujuan menilai peranan ekokardiografi dalam diagnosis infark ventrikel kanan dan membandingkan sensitivitasnya terhadap EKG dan kriteria klinis. Pada ekokardiografi, 12 dari 37 pasien (32%) menunjukkan keterlibatan ventrikel kanan. Tanda Kussmaul terjadi pada 27% pasien dan menunjukkan sensitivitas 50%, spesifisitas 88%, dan ketepatan prediksi 70%. Hantaran prekordial kanan pada EKG (V 3 R dan V 4 R) mendeteksi infark ventrikel kanan pada 30% pasien dengan sensitivitas, spesifisitas dan ketepatan prediksi masing-masing sebesar 67%, 88%, dan 73%. Gambaran ekokardiografi terdiri dari pembesaran ventrikel kanan dengan hipokinesia atau akinesia. Dilatasi dan disfungsi ventrikel kanan diperoleh dari besar relatif ventrikel kanan terhadap ventrikel kiri. Cara ini lebih sensitif dan spesifik dibandingkan gejala klinik dan EKG.

No abstract