With the present COVID‐19 vaccination drive across the world, adverse skin reactions post COVID‐19 vaccine is expected. Majority of these reactions seen were transient or local injection site reactions. However, as the larger population is being vaccinated, certain uncommon dermatological presentations including leukocytoclastic vasculitis, pityriasis rosea, and exacerbation of pre‐existing autoimmune diseases are now being reported. Among all the COVID‐19 vaccines, most of these reactions are seen with messenger ribonucleic acid‐based Pfizer/BioNTech (BNT162b2) and Moderna (mRNA‐1273) vaccine. We report two cases of leukocytoclastic vasculitis following ChAdOx1 nCoV‐19 corona virus vaccine (recombinant) that bring out potential new dermatological manifestations of recombinant corona virus vaccine being administered across the European, South American, and Asian countries. It is important for all health care workers and patients to be aware of the corona virus vaccine associated adverse cutaneous reactions.

Background: Nail involvement in psoriasis may be assessed clinically, ultrasonologically, and dermoscopically. The aim of this study was to assess the dermoscopic features of nails in psoriasis, compare them with clinical findings, and correlate them with the Nail Psoriasis Severity Index (NAPSI) score. Methods: We recruited 120 patients with psoriatic nail changes for the study. The Psoriasis Area Severity Index (PASI) was used to assess the severity of disease. Clinical and dermoscopic (DermLite DL4, ×10, polarized and non-polarized) nail examination determined NAPSI, modified NAPSI (mNAPSI), and NAPSI determined with dermoscopic findings (dermoscopic NAPSI [dNAPSI] and dermoscopic modified NAPSI [dmNAPSI]) were used to assess severity of nail involvement. Results: Subungual hyperkeratosis (50.8%) and nail plate thickening (56.7%) were the commonest clinical nail changes found, and dermoscopically, they were subungual hyperkeratosis and pitting (68.3% each). The average median with interquartile range of PASI and NAPSI scores were 7.5 [5.7-10.8] and 8.0 [6-12], respectively. NAPSI scores increased significantly with the increase in PASI scores (P < 0.001). A comparison of NAPSI and mNAPSI with dNAPSI and dmNAPSI revealed that NAPSI, mNAPSI, and dNAPSI increased significantly with an increase in PASI scores. dNAPSI scores increased significantly with increased mNAPSI and dmNAPSI, and mNAPSI and dmNAPSI were significantly good predictors of joint involvement in psoriasis. Conclusions: Dermoscopy allows for better visualization of nail findings. Evaluating NAPSI and mNAPSI scores in conjunction with dNAPSI and dmNAPSI increases their helps detect early psoriasis, detection of worsening moderate-to-severe psoriasis (PASI >10) and predict joint involvement and their severity

Context: Diagnosis of superficial mycoses in clinically doubtful cases relies on demonstration of fungal elements on a 10% potassium hydroxide (KOH) slide mount which takes 30 min to 2 h. Rapid results will lead to reduced time to diagnosis. Aims: A comparative study of conventional 10% KOH wet mount against the cellophane strip method without a mounting medium under bright-field and phase-contrast microscopy was aimed to determine the comparative efficacy of these methods in demonstrating fungal elements of superficial mycoses. Settings and Design: The study was conducted at a skin center of a tertiary care hospital between November 2019 and January 2020. Material and Methods: One hundred and fifty consecutive clinically suspect cases of superficial cutaneous mycoses were examined. Skin scrapings for 10% KOH were collected with a blunt scalpel on one slide and examined half hour later. A cellophane strip collection of squames stuck onto another slide and examined directly by bright-field and phase-contrast microscopy. Statistical Analysis Used: Descriptive and inferential statistical analysis was carried out in the present study using SPSS 22.0, and R environment version 3.2.2 was used for the analysis of the data. Chi-square/Fisher's exact test was used to find the significance of study parameters on categorical scale between two or more groups, nonparametric setting for qualitative data analysis. Fisher's exact test was used when samples were very small. Results: The mean percentage positivity for fungal hyphae as seen on KOH mount was 76%, for cellophane tape 97.33%, and under phase-contrast microscopy 97.33%. Pityriasis versicolor was detected by all three methods (100%). Tinea corporis had the least positive result on KOH mount. Conclusion: Cellophane strip method without a mounting medium adequately demonstrates fungal elements on light microscopy.

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BACKGROUND: Hypothyroidism, a major health problem, is associated with a wide range of diseases. One of the organs affected by hypothyroidism, which shows a wide range of clinical signs, is the skin. OBJECTIVES: The objective of this study was to determine various cutaneous manifestations of hypothyroidism that can be used as a diagnostic marker and may help in the early diagnosis and treatment of hypothyroidism. METHODOLOGY: A cross-sectional observational study was carried out on 100 consecutive diagnosed cases of hypothyroidism patients in the dermatology department of a tertiary care hospital in Bengaluru during June 2021–September 2021. A pretested standard pro forma was used to collect and maintain the details of the patients. The study was ethically approved by the institution. RESULTS: The majority were female (84%) and patients' age ranged from 16 to 65 years, covering all groups with 31% having comorbidities. Seventy-one percent had pruritus and 14% with urticaria, 13% with palmar and sole hyperkeratosis, 3% with burning skin symptoms, and 5% with cold skin symptoms. The majority (38%) had pruritus as an early symptom. Pruritus symptom patients were categorized into mild pruritus (25%) and moderate pruritus (75%). A significant number of patients presented with hair changes in the form of dry brittle hair in 50 patients and with other associated skin conditions which included 20 patients with melasma, 10 patients with seborrheic dermatitis, eight patients had acrochordons, four patients had vitiligo, five had polymorphic light eruptions like lesions, three patients had lichen planus, and two each had psoriasis and acne vulgaris. CONCLUSION: The present study was undertaken to know the spectrum of dermatological manifestations associated with a hypothyroid condition. It was observed the female sex, pruritis, and hair changes were common in these patients. Recognition of hypothyroidism is important to ensure that appropriate treatment is provided at the earliest, thus preventing complications.