Hipertensi dan Diabetes Mellitus (DM) merupakan penyakit komorbid COVID-19 tertinggi. Tekanan darah dan Gula darah yang tidak terkendali akan meningkatkan risiko terpapar infeksi COVID-19 dan memperburuk kondisi pasien COVID-19 sehingga mengancam kematian dengan cepat. Jenis Penelitian survey analitik ini menggunakan pendekatan case control. Analisis yang digunakan untuk mencari pengaruh kedua komorbid terhadap kejadian COVID-19 adalah Uji Regresi Logistik Binari. Populasi adalah seluruh kasus klien dewasa dan lansia yang dirawat inap kecuali ruang maternitas pada bulan Januari-Maret 2021, berjumlah 1.619. Sampel berjumlah 404 dibagi menjadi kelompok kasus Covid-19 dan kelompok kontrol. Hasil: Karakteristik berdasarkan Komorbid: Hipertensi sebesar 74 (18,3%) dan DM sebesar 106 (26,2%). Hasil analisis menunjukkan ada pengaruh komorbid hipertensi (p= 0,007; ? = 0,746; OR = 2,109) dan komorbid DM (p= 0,000; ? = -1,181; OR = 0,307) terhadap kejadian COVID-19(R2 = 0,104). Para penderita hipertensi dan diabetesi perlu lebih meningkatkan perilaku pencegahan terhadap penyakit COVID-19. Penderita hipertensi akan mengalami peningkatan ACE2 di paru, arteri, jantung sebagai reseptor yang baik bagi corona virus. Gula darah yang tinggi akan mempercepat replikasi coronavirus. Faktor ini akan mempercepat proses penyakit COVID-19

Increasing prevalence of hypertension (HT) risk factors and number of uncontrolled blood pressure in hypertensive patient still being the focus in health care, especially in nursing promotive-preventive and rehabilitative care. Complementary and alternative nursing care aims to enhance patient awareness and empowerment in unique ways, for instance Tai Chi as mind-body exercise. This study aimed to compare blood pressure and pulse responses of hypertensive individuals to 60 minutes and 30 minutes Yang style Tai Chi exercise with control group. Fifty-seven participants in the study divided to three groups (60 minutes Tai Chi, 30 minutes Tai Chi, and control group) and included by purposive sampling for eighth weeks with once a week session. Blood pressure and pulse were measured in baseline and the eighth week, then analyzed with one-way ANOVA to compare three groups at baseline and eighth week measurements. The result show that there was no significant differences at baseline for all groups (SBP: p= 0.344; DBP: p= 0.118; Pulse: p= 0.506). However, there was a significant difference at eighth-week measurement for all variables (SBP: p= 0.025; DBP: p= 0.017; Pulse: p= 0.016). The study results suggest that Tai Chi is an effective exercise to lower and maintain blood pressure and pulse levels among hypertensive patient, and thus may be potential intervention to control hypertension.