Recent technological developments in mobile brain and body imaging are enabling new frontiers of real-world neuroscience. Simultaneous recordings of body movement and brain activity from highly skillful individuals as they demonstrate their exceptional skills in real-world settings, can shed new light on neurobehavioural structure of human expertise. Driving is a real-world skill which many of us acquire on different levels of expertise. Here we ran a case-study on a subject with the highest level of driving expertise -a Formula E Champion. We studied the expert driver's neural and motor patterns while he drove a sports car in the "Top Gear" race track under extreme conditions (high speed, low visibility, low temperature, wet track). His brain activity, eye movements and hand/foot movements were recorded. Brain activity in the delta, alpha, and beta frequency bands showed causal relation to hand movements. We demonstrate, here in summary, that even in extreme situations (race track driving) a method for conducting human ethomic (Ethology + Omics) data that encompasses information on the sensory inputs and motor outputs outputs of the brain as well as brain state to characterise complex human skills.driving conditions which are hallmarks of expertise in race driving.The objective of this study was to characterise the neuromotor behaviour of expertise in the wild, with an experiment performed in real life conditions, outside a laboratory or simulator, fostering the assessment of a skilled real world task. Better understanding of expert driver's neural and motor interdependencies while facing driving challenges, can also potentially foster the development of technologies to prevent critical conditions and improve driving safety, as well as safety procedures for autonomous and semi-autonomous cars. Methods Experimental SetupThe experiment took place on the Dunsfold Aerodrome (Surrey, UK), known as the Top Gear race track. The driver (co-author) was Formula E champion, Lucas Di Grassi (Audi Sport ABT Schaeffler team), with over 15 years of professional racing experience, which include kart, Formula 3, Formula One and Formula E racing. The test drive was prescheduled for video production purposes by the racing team, who race in these conditions frequently. It enabled us this unique scientific observation of motor expertise in the wild. Although unlikely needed, emergency response units were present. A promo video of the film by Averner Films 15 is accessible here: vimeo.com/248167533.The driver was equipped with: a 32-channels wireless EEG system (LiveAmp, Brain Products GmbH, Germany) with dry electrodes (actiCAP Xpress Twist, Brain Products GmbH, Germany); binocular eye-tracking glasses (SMI ETG 2W A, SensoMotoric Instruments, Germany); and four inertial measurement units (IMUs) on his hands and feet (MTw Awinda, Xsens Technologies BV, The Netherlands); shown in Figure 1A. The car was equipped with a GPS system and a camera recording the inside of the car. The car driver assistance systems were turned off. The full a...