Introduction: Insulin resistance is a condition that underlies the development of diabetes mellitus. The prevalence of diabetes mellitus keeps rising, including in Indonesia. A higher proportion of diabetes was found in women. Physiological changes during pregnancy can cause insulin resistance that may persist until postpartum period. Lactation and nutrient like zinc may improve insulin resistance. This study aimed to measure the correlation between zinc serum level and insulin resistance of lactating mothers in Jakarta.Methods: This study used cross-sectional design, was conducted in Puskesmas Kecamatan Grogol Petamburan, West Jakarta and Puskesmas Kecamatan Cilincing, North Jakarta from February to April 2019. A total of 75 lactating mothers at 3–6 months postpartum were selected using consecutive sampling method. Zinc serum was analyzed using atomic absorption spectrophotometry (AAS) method. Insulin resistance was assessed using the homeostasis model assessment-insulin resistance (HOMA-IR).Results: Approximately 76% (n = 57) subjects had low serum zinc level. Spearman correlation test between serum zinc level and HOMA-IR was done (r = 0.003, p = 0.977). Also, correlation test between BMI and HOMA-IR (r = 0.563, p <0.001).Conclusion: No correlation was found between serum zinc level and HOMA-IR however, there was a significant moderate positive correlation between BMI and HOMA-IR.Keywords: Lactation, zinc, insulin resistance, HOMA-IR, BMI
Summary: Severe burn patients experience pronounced metabolic changes that caused hyperglycemia. Other existing metabolic conditions such as diabetes mellitus may worsen this condition. Early, adequate, and personalized nutrition therapy may result in better glycemic control and prognosis.A 44-year-old male with severe burn injury involving 27,5% total body surface area (TBSA) and type 2 diabetes mellitus (T2DM) was given early and diabetes-specific nutrition therapy to meet the recommended energy and protein needs. Lower carbohydrate contents and higher mono-unsaturated fatty acids (MUFA) were components of diabetes-specific nutrition therapy. Desirable blood glucose levels, a positive trend of albumin levels, and reduced inflammatory markers were achieved while being given this nutrition therapy. Sepsis was not diagnosed in this patient. The patient was discharged from the hospital after an improvement in clinical condition. Hyperglycemia commonly occurs in critically ill patients, especially with pre-existing T2DM. The provision of prompt and personalized nutrition therapy will improve clinical outcomes.
Background and Objectives : Deficiency of zinc is prevalent worldwide mostly in developing countries. However, its prevalence among vulnerable group such as lactating mothers is still unknown in most populations. This study aimed to determine the prevalence of zinc deficiency among lactating mothers in Jakarta and factors that influence it.Methods :A cross sectional study was conducted in Puskesmas Kecamatan Grogol Petamburan, West Jakarta and Puskesmas Kecamatan Cilincing, North Jakarta between February and April 2019. A total of 75 lactating mothers at 3–6 months postpartum, aged 20–40 years old were recruited using consecutive sampling method. Subjects were interviewed for education levels, occupation, physical activity, types of breastfeeding (exclusive or not), and numbers of parity. Dietary assessment of zinc and protein was carried using semi quantitative food frequency questionnaire (FFQ). Weight and height were measured to assess the body mass index (BMI). Blood samples were taken to analyze serum zinc concentrations. Descriptive analysis, one way ANOVA, and unpaired t-test were used, p-values ≤0.05 were considered significant.Results :The mean of serum zinc was 62.33 ± 11.89 and zinc deficiency was found in 76% of the subjects. There were no significant differences of serum zinc related to education levels, occupation, types of breastfeeding, numbers of parity, zinc intakes, protein intakes, and categories of BMI. Significant difference of serum zinc was found between levels of daily physical activity (p = 0.008) – light, moderate, and vigorous. Conclusion :Zinc deficiency was prevalent among lactating mothers in Jakarta. There was a significant difference of serum zinc between different levels of daily physical activity.
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