Breast cancer surgery can impact patients psychologically as well as organically, which can manifest as quality of life (QOL). Thirty patients, the age ranged between 25 and 60 years and the mean age 41 years. Of the 27 patients were married, a widow, and two unmarried. There was not found a difference in health related quality of life. No differences were seen in level of pain, skin sensitivity, and related problems in surgical area. Woman in mastectomy group reported stastitically more problem with their body image. Beyond that, they also have a complaint about the feelings of sexual attractiveness than woman in breast conserving surgery (BCS). Women undergoing breast conserving surgery experience more positive outcomes than women undergoing mastectomy. Women in the mastectomy groups also reported experiencing more physical problems related to their surgery. The score of CES-D was above 16 both breast conserving surgery's group and mastectomy's groups. Higher scores were associated with more symptoms. There were also no differences seen among them as measured by the MOS, there were 4 main poins consists of emotional support, real support, affection support, and good social interactions. There were also no differences seen among them as measured by the RDAS consists of 3 aspects (concensus, satisfaction, cohession). This can happen because the doctors give well support and education to all patients. Despite, the patients, their families, their partners also give support each other. The women sight of their body images was considered making well social interaction. Most of the study showed the declining of social interactions after the surgery. This happened beacuse they were apprehensive about rejection in social life.

Immunohistochemical is used to show hormone receptors on their surface. The aim of this study were to find information about immunohistochemical profile of breast cancer patient on oncology department, Moewardi Hospital, Surakarta Indonesia. A total of 1.395 cases of breast carcinoma with HER2 profile were reviewed. The mean age of the patients was 45.7 (Ranged 23-73 years old). At time of diagnosis 739 (53%) patients were under 50 years of age. The frequency of HER2 positive was higher in this group than other. The incidence of patients above 50 years of age were significancy higher in HER2 positive with 363 (47%). Ductal invasive carcinoma was the most common type of breast carcinoma (86.9%). HER-2 Positive subtype was the most common subtype in the woman breast carcinoma (43.6%), which was followed by basal like (31.3%), luminal A (16.8%) and (8.3%). The highest tumor grading, was G3 with the results 764 (54.7%). G3 got the highest results on HER2 positive with 535. We just divide the type of tumor consist of three parts (ductal, lobular, and other). In tumor type obtained the most data on ductal carcinoma with 878 (63%).

Some woman has breast tumors with higher level of HER-2. HER-2 receptor is a member of the epidermal growth factor receptor family which is gene that can play a role in the development of breast carcinoma. Normally, HER-2 receptors control breast cell grows, divides, and repair breast cell. But in pathologic conditions it makes too many copies. The aim of this study was to evaluate the expression of HER-2 in woman breast carcinoma and to compare it with Histological Type and Grade. We observed 1,395 patients with breast carcinoma. The mean age of the patients was 45.7 (Ranged 23-73 years). In this group the frequency of HER-2 positive was higher than other. The incidences of patients above 50 years were significantly higher in HER-2 positive with 363 (47%). The tumor grading showed the highest on G3 with the results 764 (54.7%). G3 got the highest results on HER-2 positive with 535. We divide the type of tumor consist of three parts (ductal, lobular, and other). Ductal carcinoma was the type of tumor with the most data with 878 (63%). The difference did not achieve statistical significance, chi square results showed >0.05. It can be concluded there was no relationship between HER-2 with histological type and grade breast cancer.

Background Neonatal respiratory distress syndrome (NRDS) is commonly diagnosed by clinical sign and symptoms, blood gas analysis, and chest x-ray. In the past, lung ultrasound (LUS) was not standard for NRDS examination. Many studies show that ultrasound diagnostic tool for NRDS is accurate, reliable, low cost, easy to use, and safe because due to no ionizing radiation. Objective To determine the sensitivity and specificity of LUS in diagnosing NRDS. Methods This meta-analysis study was conducted LUS as a diagnostic tool for NRDS. Inclusion criteria were all studies from PubMed, Embase, and The Cochrane Library, without any limitation on published journals, as well as using keywords or search terms of ultrasound, neonatal, and respiratory distress syndrome. Statistical analysis was undertaken using MedCalc® version 18.2 software. Results Seven studies with a total of 580 patients met the inclusion criteria. Proportional meta-analysis obtained random effects models, with total sensitivity of LUS was 97.2% (95% CI for I2 74.24 to 92.88; P<0.0001) and specificity of LUS was 94.8% (95% CI for I2 88.60 to 98.03; P<0.00001). Conclusion Lung ultrasound should be considered as a diagnostic tool for NRDS because it is high in sensitivity and specificity, inexpensive, safe, as well as limited radiation exposure.