Introduction: Multiple sclerosis is a chronic inflammatory demyelinating disease associated with neurological disability. Clinical features include motor, cerebellar, visual, and sensory function alterations, as well as psychiatric comorbidities, such as depression, anxiety, and irritability. There is little literature available on the quality of life of patients and their caregivers.Objective: To assess the quality of life of patients with multiple sclerosis and their caregivers in Colombia given that there is no information on the subject in this particular population to establish comprehensive management plans.Materials and methods: We used the MusiQol and CareQol questionnaires and the Beck Depression Inventory. A prospective analytical observational protocol was designed to include patients aged 18 to 65 years with a diagnosis of relapsing-remitting multiple sclerosis between October, 2014, and October, 2015, at the Hospital Universitario San Ignacio. We evaluated quantitative variables and Spearman correlations. The data analysis was carried out with Student t and Mann-Whitney U tests.Results: A total of 55 patients with relapsing-remitting multiple sclerosis participated in the study. Chronic fatigue was the most common comorbidity in 27%. The MusiQol questionnaire revealed a good basal quality of life, which remained at similar levels in the follow-ups at six and 12 months. Quality of life was good during the study since there were no statistically significant differences between baseline and follow-up MusiQol scores. Good quality of life was also observed in caregivers.Conclusions: The quality of life of several Colombian patients diagnosed with multiple sclerosis was very good. This positive result was also observed in caregivers as evidenced by the results of the CareQol questionnaire. We also observed and indicated an inversely proportional correlation between the Expanded Disability Status Scale and the quality of life indexes.

En este artículo se analizan las prácticas de lectura y escritura de la clase de biología, en el grado séptimo de dos instituciones. El objetivo de esta investigación fue conocer cómo son las prácticas de literacidad en esta asignatura, y qué las distingue en relación al campo disciplinar, de ahí que este estudio se ubique en el marco de estudio de la literacidad disciplinar. Se trata de observar y analizar las prácticas de lectura y escritura escolares articuladas al mundo social, a partir de determinadas formas de actuar, sentir, creer y pensar. Se realizaron diez observaciones y se entrevistaron a las profesoras del área. A partir de ello, se identificaron las prácticas y los eventos letrados más comunes, los cuales fueron interpretados a través de las siguientes categorías: literacidad disciplinar, evento letrado, comunidad de discurso y dominio del área por parte del estudiante. De otro lado, se encontró, entre las concepciones de las profesoras acerca de la importancia de la lectura y la escritura, que dichas prácticas se asocian al uso de la lectura como recurso de investigación; al uso de la escritura como medio de producción desde conceptos interiorizados y la enseñanza de la biología como una posibilidad de formar el pensamiento científico.