As measured by the online survey tool, self-reported episode number for the intervention group declined by 57% in the last 30 days of supplement use. The average episode duration decreased from 616 minutes to 170 minutes and the average combined severity decreased by 30%. In the cognitive, stress and sleep scales, there was a positive correlation between decreasing migraine symptoms and improvement in these three areas. The control group had no statistically significant changes. CONCLUSIONS: In this comparison study, a decrease in migraine episodes, duration and severity was positively linked to improved quality of life measures for migraineurs. Consumption of a proprietary high concentration ingredient complex using phytonutrients produced significant improvements in the spectrum of symptoms across a broad domain of the measured variables.