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Objective: To investigate the effect of gonadotropin, sex hormone levels and insulin resistance (IR) on thyroid functions and thyroid volume (TV) in polycystic ovary syndrome (PCOS). Subjects and methods: Sixty nine new diagnosed PCOS patients (age 24.82 ± 6.17) and 56 healthy control female (age 26.69 ± 5.25) were involved to the study. Fasting plasma glucose, lipid profile, insulin, thyroid stimulating hormone (TSH), free thyroxine (fT4), estradiol (E2), luteinizing hormone (LH), follicle stimulating hormone levels and urine iodine were measured in all participants. Thyroid and pelvic ultrasound were performed in all participants. Results: Insulin, HOMA-IR, LH, E2 and TV were higher in PCOS group (p < 0.05). TV was significantly higher in PCOS patients with IR compared to non-IR PCOS patients (p < 0.001), while TSH, fT4, and urine iodine levels were similar between these groups (p > 0.05). There was a negative correlation between E2 and TSH (p < 0.05) and a positive correlation between TSH and TV (p < 0.05). There was a significant positive correlation between TV and LH, insulin, HOMA-IR (p < 0.05). Conclusion: This study showed that TV was increased in patients with insulin resistance but differences in TSH and LH levels may affect TV changes as well. Arch Endocrinol Metab. 2017;61(2):145-51.

ÖzAMAÇ: Son dönem böbrek yetmezliğinin en seçkin tedavi yöntemi böbrek naklidir. Ancak günümüzde, ülkemizde böbrek nakli sayısı istenilen düzeye ulaşamamıştır. Biz bu çalışmada, kronik hemodiyaliz hastalarının böbrek nakli konusundaki istekliliklerini, bilgi düzeyini ve beklentilerini ölçmeyi amaçladık. GEREÇ ve YÖNTEMLER:18 yaş üzeri ve en az 3 ay hemodiyaliz tedavisi gören hastalar çalışmaya alındı. Hastalara 23 soru soruldu ve cevapları analiz edildi. BULGULAR:Hastaların böbrek nakli konusunda yeterince bilgi sahibi olmadığını, buna rağmen nakil konusunda istekli olduklarını ve böbrek nakli olma konusunda hekimlerden ve toplumdan beklentileri olduğunu tespit ettik. SONUÇ:Hemodiyaliz hastaları böbrek nakli konusunda bilgilendirilmeli ve teşvik edilmelidir. ANAhTAR SÖzcükLER: Hemodiyaliz, Böbrek nakli, Bakış açısı ABSTRAcTOBJEcTIVE: Renal transplantation is the best treatment method of end-stage renal disease. Unfortunately, renal transplantation rates have not reached the desired level yet in our country. In this study, we aimed to evaluate the willingness, knowledge levels and expectation of hemodialysis patients about renal transplantation. MATERIAL and METhODS:Patients older than 18 years of age and treated with hemodialysis for at least 3 months were enrolled in the study. Twenty-three questions were asked and the answers evaluated. RESULTS:We determined that most patients have insufficient information about transplantation but are willing to undergo kidney transplantation and have expectations from physicians and the society about transplantation.

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