A B S T R A C TTuberculosis involving spinal cord in the form of intramedullary tuberculoma is uncommon, and the concurrent occurrence of cranial and intramedullary tuberculomas is extremely rare. We report a case of disseminated tuberculoma involving brain and spinal cord with miliary tuberculosis in a 32-year-old male presenting with fever, cerebellar signs and motor weakness of both upper and lower extremities. Based on magnetic resonance imaging and polymerase chain reaction, we diagnosed as tuberculoma. He completely recovered with conventional antituberculous treatment and steroids. The follow-up of the patient showed disappearance of signs and symptoms.

Progressive supranuclear palsy is a neurodegenerative disorder. The cause of PSP is unknown. It is under diagnosed by physician and neurologist. Clinical feature of PSP resemble with parkinsonism, carticobasal degeneration, multiple system atrophy and multi infarct state. Due to common clinical feature with Parkinsonism, carticobasal degeneration, multiple system atrophy neuroimaging that can help to diagnose PSP. MRI play pivotal role in confirming the diagnosis.