Background
Coronavirus disease 2019 (COVID‐19) in children is milder than in adults. Household virus exposure may affect clinical severity. We aimed to determine the household contact history of patients and its influence on the clinical stage.
Methods
One hundred and seventy‐three pediatric patients with COVID‐19 as diagnosed with positive real‐time polymerase chain reaction for severe acute respiratory syndrome coronavirus‐2 aged 1 month to 18 years were included. Demographic data, laboratory and clinical findings, and the history of household contact of the patients were obtained. They were classified according to their clinical stage as mild or moderate‐severe.
Results
Sixty patients (34.7%) were asymptomatic, and 113 were symptomatic (65.3%). Of the 173 patients, 138 (79.8%) had at least one family member in the household who was diagnosed as having COVID‐19. Hemoglobin, absolute neutrophil count, and absolute neutrophil count /absolute lymphocyte count ratio decreased significantly in patients with household contact. The presence of a household contact did not have a significant effect on the presence of symptoms, clinical course, age, and the sex of the patients. The need for hospitalization was less in the group that had household contact. Being 0–12 months, being female, and being a patient without household contact were independent factors associated with higher hospitalization ratios in logistic regression analysis.
Conclusions
In this study, we found that household contact history did not significantly affect presenting symptoms and clinical course. We detected the rate of hospitalization to be less in the group with only household contact.
In our study, the changing epidemiology of
Candida
species in candidemia in children was evaluated. The dominance of
Candida parapsilosis
species in the changing epidemiology was remarkable. We found that fluconazole resistance was high in both parapsilosis and nonparapsilosis groups. Updating local epidemiologic data at certain intervals in candidemia cases is important in determining both the changing epidemiology and empirical antifungal agents.
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