Copper catalysed Chan–Lam N-arylation of ferrocenyl 2,4-thiazolidinedione conjugates is described.

A new series of ferrocenyl sugar-triazole conjugates, derived from D-xylose, D-ribose and D-galactose, linked by a 2,4thiazolidinedione moiety, has been prepared. Facile 1,3-dipolar-Huisgen coupling reactions of the respective sugar azides with the ferrocenyl 2,4-thiazolidinedione alkyne units give the corresponding conjugates. These conjugates have been characterized by various spectroscopic techniques, including UV/Vis [a] Synthesis and CharacterizationThe compound 2,4-thiazolidinedione was prepared by a literature method [26] and was condensed with ferrocene-carboxaldehyde 1, under Knoevenagel conditions, to form compound 2, Scheme 1. Synthesis of ferrocenyl 2,4-thiaolidinedione alkyne.Scheme 2. Synthesis of ferrocenyl 2,4-thiazolidinedione sugar-triazole conjugates 5a-g.Eur. J. Inorg. Chem. 2018, 1571-1580 www.eurjic.org

This article describes the synthesis, optoelectronic properties and anti‐inflammatory activities of a series of seven ferrocenyl ester‐linked 4‐arylidene‐5‐imidazolinone conjugates. Three different types of ortho‐, meta‐ and para‐substituted ferrocenyl esters have been prepared. Their UV–Vis spectra and electrochemical studies are described. The structure of one of the conjugates was confirmed by single‐crystal X‐ray diffraction study. These conjugates exhibited moderate anti‐inflammatory activities.