Objectives
While uncommon in the population at large, peritonsillar abscess (PTA) is a common subject of ENT referrals. Missed or uncertain diagnosis is a source of concern for non‐specialist referrers. In line with the NHS England Second Sepsis Action Plan, we aimed to develop a predictive score for the presence of PTA. This would help to improve non‐specialist colleagues’ diagnostic certainty as well as to support ENT surgeons’ triage of these referrals.
Design
Prospective, multicentre observational study.
Setting
Primary and secondary care.
Participants
Patients >16 years with symptoms of sore throat.
Data
We prospectively collected comprehensive data on patient demographics, symptoms and clinical status. We documented whether the patient had aspiration‐proven PTA or not. We performed binary logistic regression analysis, iterative development of a predictive score which we validated internally.
Results
100 patients were included (46 PTA and 54 tonsillitis). Five variables added significantly to the logistic regression model: unilateral sore throat; trismus; male gender; pharyngeal voice change; and uvular deviation. Using the odds ratio outputs, we developed the Liverpool Peritonsillar abscess Score (LPS) iteratively. We validated the latest (third) iteration of the LPS internally (ie, on the same sample), yielding sensitivity 96%; specificity 85%; positive predictive value 85%; and negative predictive value 96%. The area under the receiver operating characteristics (AUROC) curve was 0.970.
Conclusions
We have developed the first predictive score for PTA based on symptoms and signs that do not require the user to have specialist experience. Its high negative predictive value may be particularly helpful to non‐specialist colleagues.
Background:
Dog bite injuries are a common presentation to Accident and Emergency. In the United Kingdom ~250,000 people attend emergency units each year as a result of dog wounds. Currently, there is a lack of consistency in the approach and management of such wounds across plastic surgery units in the United Kingdom.
Method:
A retrospective review of medical record of patients who were admitted under the care of the Plastic Surgery Department at University Hospital North Midlands NHS Foundation Trust with dog-bite wounds between January and December 2018.
Results:
Of the 69 patients that were included in the study, 14 (20%) of them had been prescribed antibiotics that were ineffective and against antimicrobial guidelines. Following liaison with the antimicrobial governance team and input from NICE guidelines, the trust’s MicroGuide Antibiotic Prescribing Guidelines App was updated. A reaudit from November 2019 to February 2020 showed that there was 100% compliance with guidance.
Conclusion:
Updating the University Hospital of North Midlands NHS Trust’s MicroGuide antibiotic prescribing guidelines for the treatment of dog-bite injuries resulted in 100% of patients being treated with the correct antibiotic. Given the polymicrobial nature of animal-bite wounds, and the high levels of resistance demonstrated by organisms commonly found in such injuries, this increased compliance with guidelines helps minimize patient suffering, morbidity, length of stay, and disability, while reducing costs incurred. The intervention should be implemented within other units within the United Kingdom who similarly lack clear, detailed guidelines, in order to maximize treatment continuity and patient outcomes nationwide.
Peritonsillar abscesses (PTA, also known as quinsies) are a frequently occurring presentation to emergency departments and represent a common reason for referral to an ENT service. Management options include drainage of the abscess and antibiotic therapy. Without intervention, PTA can develop into deep neck space infections (DNSI) which carry significant morbidity and mortality. 1 Patients who undergo drainage of their PTA have been shown to experience quicker resolution of symptoms. 2
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